[24F] Experiencing prolonged fatigue and mood changes

Patient Description

A 24-year-old female reports experiencing constant fatigue and lack of energy for several months, accompanied by intense feelings of sadness. These symptoms have been persistent and are the most intense she has experienced. Sleeping provides some relief from the sadness. She has noticed eating less but gaining weight, along with irregular menstrual cycles and feeling warm consistently. There is a family history of depression. She was diagnosed with depression and anxiety a year ago and is currently taking Prozac at a dosage of 30 mg daily. Additionally, she takes acetaminophen as needed, a cranberry supplement, and birth control. No known allergies to medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential explanations for what you might be experiencing:

  1. Depression and Anxiety: Your ongoing feelings of sadness, fatigue, and changes in appetite and weight could be related to your depression and anxiety. These conditions can significantly impact energy levels and mood, and it's not uncommon for symptoms to fluctuate in intensity over time.

  2. Thyroid Dysfunction: Although you haven't had your thyroid function tested, some of your symptoms, such as fatigue, weight gain despite eating less, and menstrual irregularities, could suggest a thyroid issue. Hyperthyroidism, for example, can cause feelings of warmth and changes in weight and appetite.

  3. Medication Side Effects: Prozac (fluoxetine) can sometimes cause side effects like fatigue, changes in weight, and menstrual irregularities. It's important to discuss any concerns about side effects with your healthcare provider.

What you can do

Addressing Fatigue and Sadness:

  • Consult Your Doctor: It's important to discuss your symptoms with your healthcare provider, especially since they have intensified. They may want to adjust your medication or explore other treatment options.
  • Lifestyle Adjustments: Try to maintain a regular sleep schedule, engage in light physical activity, and eat a balanced diet to help manage your energy levels and mood.
  • Symptom Tracking: Use MDandMe to journal your symptoms, track your progress, and share this information with your healthcare provider. This can help in identifying patterns and making informed decisions about your treatment.

Exploring Thyroid Health:

  • Consider Testing: Talk to your doctor about the possibility of testing your thyroid function to rule out any underlying issues.
  • Monitor Symptoms: Keep an eye on any new symptoms or changes in your current symptoms, and report these to your healthcare provider.

What you should look out for

  • Worsening Symptoms: If you notice your symptoms getting worse, or if you experience new symptoms like severe mood changes, suicidal thoughts, or significant changes in your physical health, seek medical attention promptly.
  • Side Effects: Be aware of any potential side effects from your medications and discuss these with your doctor, especially if they impact your daily life.

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and personalized treatment plan.

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2 mo ago

People Also Ask


Can depression and anxiety cause physical symptoms like fatigue and weight changes?

Yes, depression and anxiety can cause a range of physical symptoms, including fatigue, changes in appetite, and weight fluctuations. These conditions can affect energy levels and overall physical health.


What are common symptoms of thyroid dysfunction that I should be aware of?

Common symptoms of thyroid dysfunction include fatigue, weight changes, feeling unusually warm or cold, and menstrual irregularities. It's important to discuss these symptoms with your doctor for proper evaluation.


Could my medication, Prozac, be contributing to my symptoms?

Prozac (fluoxetine) can have side effects such as fatigue, weight changes, and menstrual irregularities. It's important to discuss any concerns about side effects with your healthcare provider to determine if your medication needs adjustment.


How can I effectively track my symptoms to discuss with my healthcare provider?

You can track your symptoms by keeping a daily journal of your mood, energy levels, sleep patterns, and any physical changes. Apps like MDandMe can help organize this information, making it easier to share with your healthcare provider for better management of your condition.


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