[24F] Experiencing nausea, fatigue, and significant weight loss

Patient Description

A 24-year-old female reports a persistent inability to eat due to nausea at the thought of food, accompanied by significant fatigue and an 86-pound weight loss over the past 5 months. The patient denies any abdominal pain, changes in bowel habits, or difficulty swallowing. There have been no recent travels or exposure to new environments, chemicals, or substances. The patient's family history includes gastrointestinal disorders. Her medical history is significant for tachycardia and a seizure disorder, with an allergy to Risperdal. There have been no changes in her menstrual cycle.

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Arora's Assessment

What might be happening

It sounds like you are experiencing a combination of symptoms that could be related to several potential issues. Here are some possibilities:

  1. Gastrointestinal Disorders: Your significant weight loss, nausea, and loss of appetite over the past 5 months could be indicative of a gastrointestinal issue such as gastritis, peptic ulcer disease, or even more chronic conditions like Crohn's disease or celiac disease. These conditions can affect your ability to eat and absorb nutrients properly.

  2. Metabolic or Endocrine Disorders: Conditions such as hyperthyroidism or diabetes can cause symptoms like weight loss, fatigue, and changes in appetite. These conditions affect your metabolism and energy levels.

  3. Mental Health Concerns: Sometimes, symptoms like loss of appetite and fatigue can be related to mental health conditions such as depression or anxiety. These conditions can significantly impact your daily life and physical health.

  4. Infections or Chronic Illnesses: Although your recent COVID-19 test was negative, other infections or chronic illnesses could cause prolonged symptoms like fatigue and weight loss.

What you can do

Loss of Appetite and Weight Loss:

  • It's important to see a healthcare provider as soon as possible to determine the underlying cause of your symptoms. They may recommend blood tests, imaging studies, or referrals to specialists.
  • In the meantime, try to eat small, frequent meals that are high in calories and nutrients. Nutritional shakes or smoothies can be a good option.
  • Keep a journal of your symptoms, including what you eat and how you feel afterward. This can help your healthcare provider understand your condition better. You can use MDandMe to track your symptoms and share this information with your provider.

Fatigue:

  • Ensure you are getting enough rest and prioritize sleep hygiene. This includes maintaining a regular sleep schedule and creating a restful environment.
  • Engage in light physical activity, such as walking, if you feel up to it. This can help boost your energy levels.
  • Stay hydrated and consider electrolyte-rich drinks if you're experiencing fatigue.

What you should look out for

Given the severity and duration of your symptoms, it's important to seek medical care promptly. Reasons to seek care more urgently include:

  • Severe abdominal pain or discomfort
  • Persistent vomiting or inability to keep fluids down
  • Signs of dehydration, such as dizziness, dry mouth, or decreased urination
  • Any new or worsening symptoms

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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1 mo ago

People Also Ask


What are some common gastrointestinal disorders that could cause significant weight loss and nausea?

Common gastrointestinal disorders that could cause significant weight loss and nausea include gastritis, peptic ulcer disease, Crohn's disease, and celiac disease. These conditions can interfere with digestion and nutrient absorption, leading to weight loss and nausea.


How can metabolic or endocrine disorders affect appetite and weight?

Metabolic or endocrine disorders, such as hyperthyroidism or diabetes, can alter metabolism and energy levels, leading to changes in appetite and weight. Hyperthyroidism can increase metabolism, causing weight loss, while diabetes can affect how the body processes glucose, impacting appetite and energy.


Can mental health conditions like depression or anxiety lead to physical symptoms such as fatigue and loss of appetite?

Yes, mental health conditions like depression and anxiety can manifest physically, leading to symptoms such as fatigue and loss of appetite. These conditions can affect motivation, energy levels, and interest in food, contributing to weight loss and fatigue.


What are some signs that indicate the need for urgent medical care in cases of severe weight loss and fatigue?

Signs that indicate the need for urgent medical care include severe abdominal pain, persistent vomiting, inability to keep fluids down, signs of dehydration (such as dizziness, dry mouth, or decreased urination), and any new or worsening symptoms. These could indicate a serious underlying condition that requires prompt attention.


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