[22F] With nausea, late period, and abdominal cramps post-Plan B

Patient Description

A 22-year-old female has been experiencing nausea, a late menstrual period, and lower abdominal cramps since taking Plan B in the third week of August. The cramps, rated 7.5/10 in severity, started on August 31st, occur every other day, and last for about 30 seconds to 1 minute. Sleeping helps alleviate the cramps. The patient also reports sore nipples for the past week, described as mild, and emotional fluctuations, including sudden crying, anger, and calmness. Her last menstrual period was on August 14th, and she had spotting for two days on August 22nd and 23rd. A pregnancy test was negative. The patient has been smoking weed frequently but stopped on September 3rd and consumed alcohol and used hookahs on September 1st and 2nd. She experienced a headache, likely due to not eating and hot weather. No pre-existing conditions, chronic illnesses, or medications reported.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Hormonal Changes: Taking Plan B (emergency contraception) can cause temporary hormonal imbalances, which might explain your late period, spotting, cramps, nausea, sore nipples, and emotional changes. Plan B contains a high dose of levonorgestrel, which can disrupt your menstrual cycle and cause side effects similar to early pregnancy symptoms.

    • Treatment: These side effects usually resolve on their own within a few weeks. If your period does not return to normal or if symptoms persist, consult a healthcare provider.
  • Early Pregnancy: Despite a negative pregnancy test, it is still possible to be pregnant, especially if the test was taken too early. Symptoms like nausea, cramps, sore nipples, and emotional changes can be early signs of pregnancy.

    • Treatment: If you suspect pregnancy, take another pregnancy test a week after the first one or consult a healthcare provider for a more accurate test.
  • Stress and Lifestyle Factors: Frequent smoking, alcohol consumption, and partying can contribute to physical and emotional symptoms. Stress and lifestyle changes can also affect your menstrual cycle and overall well-being.

    • Treatment: Reducing stress, maintaining a healthy lifestyle, and avoiding substances like alcohol and marijuana can help alleviate symptoms.

What you can do

  1. Monitor Your Symptoms: Keep track of your symptoms, including the timing and severity of cramps, nausea, and emotional changes. Use the MDandMe journal to record your symptoms and any potential triggers.
  2. Take Another Pregnancy Test: If your period remains late, consider taking another pregnancy test a week after the first one. Follow the instructions carefully for the most accurate result.
  3. Stay Hydrated and Eat Well: Ensure you are drinking plenty of water and eating a balanced diet. Avoid skipping meals, as this can contribute to headaches and nausea.
  4. Rest and Relax: Try to get enough sleep and engage in activities that help you relax, such as gentle exercise, reading, or meditation.
  5. Avoid Substances: Continue to avoid smoking, alcohol, and other substances that might exacerbate your symptoms.
  6. Consult a Healthcare Provider: If your symptoms persist or worsen, or if you have concerns about your menstrual cycle or potential pregnancy, seek advice from a healthcare provider.

What you should look out for

  • Severe Pain or Bleeding: If you experience severe abdominal pain, heavy bleeding, or any unusual discharge, seek medical attention immediately.
  • Persistent Symptoms: If your symptoms do not improve or if you continue to experience nausea, cramps, or emotional changes, consult a healthcare provider.
  • Positive Pregnancy Test: If a subsequent pregnancy test is positive, schedule an appointment with a healthcare provider to confirm the pregnancy and discuss next steps.

Remember, while I can provide information and suggestions, I am not a doctor. It is important to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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3 mo ago


People Also Ask


Can taking Plan B affect my menstrual cycle and cause symptoms like nausea and cramps?

Yes, taking Plan B can cause temporary hormonal imbalances, leading to changes in your menstrual cycle, such as a late period, spotting, nausea, cramps, and other symptoms similar to early pregnancy. These side effects usually resolve within a few weeks.


Is it possible to be pregnant even if a pregnancy test is negative?

Yes, it is possible to be pregnant even if a pregnancy test is negative, especially if the test was taken too early. It is recommended to take another test a week later or consult a healthcare provider for a more accurate test.


How can lifestyle factors like smoking and alcohol consumption affect my menstrual cycle and symptoms?

Lifestyle factors like frequent smoking, alcohol consumption, and stress can contribute to physical and emotional symptoms and may affect your menstrual cycle. Reducing stress and avoiding substances can help alleviate symptoms.


What should I do if my symptoms persist or worsen after taking Plan B?

If your symptoms persist or worsen, it is important to consult a healthcare provider. They can provide a formal diagnosis and appropriate treatment. Additionally, if you experience severe pain or heavy bleeding, seek medical attention immediately.


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