[20M] With radiating pain, limb jerking, and systemic symptoms

Patient Description

A 20-year-old male presents with pain radiating from the left shoulder down to the ring and pinky fingers, as well as pain in the left lower leg, primarily in the foot and ankle. The pain is described as deep and dull, accompanied by jerking movements of the limbs occurring two to five times a day, mostly in the afternoon. The patient also reports nausea and sensations of feeling hot and cold without fever. These symptoms have been present for over 24 hours, with tingling and burning sensations in the hands and feet occurring on and off for about a year. Over-the-counter medications and heat/cold compresses have not provided relief. The patient's family history includes neuropathy related to cancer. Current medications include Amitriptyline, Atenolol, Qulipta, Tizanidine, Duloxetine, and Nextstellis. The patient's rheumatologist suspects drug-induced lupus, supported by a positive ANA test. The patient plans to see a doctor for further evaluation and management.

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Arora's Assessment

What might be happening

Based on the symptoms and information you've provided, here are some possibilities:

  1. Ulnar Nerve Entrapment: The pain radiating from your left shoulder to your ring and pinky fingers could be due to compression of the ulnar nerve. This condition can cause pain, tingling, and weakness in the affected arm and hand. Treatment often involves physical therapy, splinting, or, in some cases, surgery.

  2. Peripheral Neuropathy: Given your family history and symptoms like tingling and burning sensations in your hands and feet, peripheral neuropathy is another possibility. This condition involves damage to the peripheral nerves and can cause pain, tingling, and muscle weakness. Treatment may include medications, lifestyle changes, and addressing any underlying conditions.

  3. Fibromyalgia: Your rheumatologist's consideration of fibromyalgia is also relevant. This condition is characterized by widespread pain, fatigue, and tenderness. Treatment typically involves a combination of medication, lifestyle changes, and therapies such as physical therapy and cognitive behavioral therapy.

  4. Drug-Induced Lupus: With a positive ANA test and your rheumatologist's suspicion, drug-induced lupus could be a possibility. This condition is triggered by certain medications and can cause symptoms similar to systemic lupus erythematosus. Symptoms usually resolve once the medication is discontinued.

What you can do

Pain and Tingling:

  • Continue documenting your symptoms in the MDandMe journal, noting any changes or patterns.
  • Follow your doctor's recommendations for managing pain, which may include medications, physical therapy, or lifestyle modifications.
  • Avoid activities that exacerbate your symptoms and consider gentle stretching exercises.

Fibromyalgia:

  • Engage in regular low-impact exercise, such as walking or swimming, to help manage symptoms.
  • Practice stress-reduction techniques, such as mindfulness or yoga, to improve overall well-being.
  • Ensure you get adequate sleep and maintain a consistent sleep schedule.

Drug-Induced Lupus:

  • Discuss with your doctor the possibility of adjusting or discontinuing any medications that may be contributing to your symptoms.
  • Follow up with any additional tests or evaluations your doctor recommends to monitor your condition.

What you should look out for

  • Worsening Symptoms: If your pain, tingling, or other symptoms worsen, contact your healthcare provider for further evaluation.
  • New Symptoms: Be vigilant for any new symptoms, such as joint swelling, rashes, or unexplained fevers, and report them to your doctor.
  • Severe Reactions: Seek immediate medical attention if you experience severe reactions, such as difficulty breathing, chest pain, or sudden weakness.

Remember, it's important to work closely with your healthcare provider to determine the best course of action for your specific situation. If you have any further questions or need assistance, feel free to reach out!

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People Also Ask


What is ulnar nerve entrapment and how is it treated?

Ulnar nerve entrapment occurs when the ulnar nerve is compressed, often at the elbow or wrist, leading to pain, tingling, and weakness in the arm and hand. Treatment may include physical therapy, splinting, avoiding activities that worsen symptoms, and in some cases, surgery.


What are the common symptoms and treatments for peripheral neuropathy?

Peripheral neuropathy involves damage to the peripheral nerves, causing symptoms like tingling, burning sensations, and muscle weakness. Treatment focuses on managing symptoms and may include medications, lifestyle changes, and addressing any underlying conditions.


How is fibromyalgia diagnosed and managed?

Fibromyalgia is diagnosed based on a history of widespread pain, fatigue, and tenderness. Management typically involves a combination of medications, lifestyle changes, regular low-impact exercise, stress-reduction techniques, and therapies such as physical therapy and cognitive behavioral therapy.


What is drug-induced lupus and how can it be resolved?

Drug-induced lupus is a condition triggered by certain medications, causing symptoms similar to systemic lupus erythematosus. Symptoms usually resolve once the offending medication is discontinued, but it's important to consult with a healthcare provider before making any changes to medication.


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