[20F] Experiencing missed period with negative pregnancy test, nausea, and vomiting

Patient Description

A 20-year-old female has reported a missed period for the last 6 weeks with a negative pregnancy test. She experienced a miscarriage in February, had a normal period in March, but missed her period in April. Alongside the missed period, she is experiencing nausea, vomiting, and fatigue. She denies any significant stress, lifestyle changes, or weight fluctuations recently. Additionally, she has severe abdominal pain and persistent vomiting but no unusual vaginal bleeding or discharge, dizziness, or fainting. The patient does not use recreational drugs, alcohol, or tobacco products and is not on any medications. No pre-existing conditions or chronic illnesses were reported.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are a few possibilities:

  • Hormonal Imbalance: This can be caused by various factors such as stress, changes in weight, or certain medical conditions. It can lead to irregular periods and symptoms like fatigue and nausea.

    • Treatment typically involves addressing the underlying cause and may include hormonal therapies.
  • Polycystic Ovary Syndrome (PCOS): This is a condition that affects a woman's hormone levels. Women with PCOS produce higher-than-normal amounts of male hormones, which can cause missed or irregular periods, along with other symptoms.

    • Treatment for PCOS usually involves lifestyle changes and medication to manage symptoms and prevent complications.
  • Thyroid Disorders: Both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can cause menstrual irregularities, along with symptoms like fatigue and changes in weight.

    • Treatment usually involves medication to restore normal thyroid function.

Please note that these are possibilities based on the information you've provided and you should see a healthcare provider for a formal diagnosis.

What you can do

  1. Schedule an appointment with a healthcare provider. They can perform tests to determine the cause of your missed period and other symptoms.
  2. Keep track of your symptoms. This can help your healthcare provider make a diagnosis.
  3. Try to maintain a healthy lifestyle. Regular exercise, a balanced diet, and adequate sleep can help regulate your menstrual cycle.

What you should look out for

Seek immediate medical attention if you experience:

  • Severe abdominal pain
  • Persistent vomiting
  • Unusual vaginal bleeding or discharge
  • Dizziness or fainting

Remember, this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for accurate information.

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7 mo ago


People Also Ask


What could cause a missed period with a negative pregnancy test?

A missed period with a negative pregnancy test can be caused by factors such as stress, hormonal imbalances, thyroid disorders, or conditions like Polycystic Ovary Syndrome (PCOS). It's important to consult a healthcare provider for a proper diagnosis.


How can hormonal imbalances affect menstrual cycles?

Hormonal imbalances can disrupt the regularity of menstrual cycles, leading to missed or irregular periods. They can also cause symptoms like fatigue, nausea, and mood changes. Treatment often involves addressing the underlying cause and may include lifestyle changes or hormonal therapies.


What are the symptoms and treatment options for Polycystic Ovary Syndrome (PCOS)?

PCOS is a condition characterized by hormonal imbalances that can lead to irregular periods, excess hair growth, acne, and weight gain. Treatment typically involves lifestyle changes, such as diet and exercise, and medications to manage symptoms and prevent complications.


How do thyroid disorders impact menstrual health?

Thyroid disorders, such as hypothyroidism and hyperthyroidism, can cause menstrual irregularities, including missed or heavy periods. They can also lead to symptoms like fatigue, weight changes, and mood swings. Treatment usually involves medication to normalize thyroid hormone levels.

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