[19F] With severe sore throat, swollen tonsils, and lymphadenopathy

Patient Description

A 19-year-old female presents with a severe sore throat and swollen tonsils that have persisted for 4 months, significantly impacting her ability to eat and drink. She reports relief with prescribed oral steroids and Tylenol. The patient also has prominent, tender swollen lymph nodes in the neck, but none in the armpits or groin. She has experienced weight fluctuations, difficulty breathing and swallowing, night sweats, and unexplained fevers. Her medical history includes anemia diagnosed 4 years ago and two recent episodes of pneumonia within the last 4 months. No known drug allergies. She is currently using the Nuva Ring for birth control and is not on any other medications.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Chronic Tonsillitis: This is an infection of the tonsils that can cause symptoms such as a long-term sore throat, swollen tonsils, and swollen lymph nodes in the neck. It can be caused by various types of bacteria or viruses.

    • Treatment typically involves antibiotics to clear the infection. In severe or recurrent cases, a tonsillectomy (surgical removal of the tonsils) may be recommended.
  • Mononucleosis (Mono): Also known as the "kissing disease," this is a viral infection caused by the Epstein-Barr virus. It can cause a severe sore throat, swollen tonsils, swollen lymph nodes, and fever. It can also cause fatigue, which might explain your weight fluctuations.

    • Treatment for mono is mainly supportive, including rest, hydration, and over-the-counter remedies for pain and fever.
  • Lymphoma: This is a type of cancer that begins in the lymphatic system. The symptoms can include swollen, painless lymph nodes in the neck, unexplained weight loss, and night sweats. However, lymphoma is rare, especially in people your age, and there are many more common causes of these symptoms.

    • Treatment for lymphoma can include chemotherapy, radiation therapy, and other therapies.

Please remember that these are only possibilities. You should see a healthcare provider for a formal diagnosis.

What you can do

You should make an appointment with a healthcare provider as soon as possible to discuss your symptoms. They may want to perform some tests, such as a throat swab to check for bacteria, blood tests to look for signs of mono or other infections, or imaging tests to examine your lymph nodes.

In the meantime, continue to take over-the-counter pain relievers as needed for your throat pain. Try to stay hydrated and eat nutritious foods as much as you can, even if it's uncomfortable. Warm liquids like tea or soup might be easier to swallow.

What you should look out for

You should seek immediate medical attention if you develop any of the following:

  • Difficulty breathing or swallowing that gets worse
  • High fever (over 103°F or 39.4°C)
  • Severe weakness or fatigue
  • Severe or worsening pain
  • Any other symptoms that are severe or concerning to you

Remember, I'm an AI and this advice is based on the information you've given me. It's always important to consult with a healthcare provider for an accurate diagnosis and treatment.

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11 mo ago

People Also Ask


What are the common causes of a persistent sore throat and swollen tonsils?

Common causes of a persistent sore throat and swollen tonsils include chronic tonsillitis, viral infections like mononucleosis, and less commonly, conditions like lymphoma. Bacterial infections may require antibiotics, while viral infections often need supportive care.


How is mononucleosis diagnosed and treated?

Mononucleosis is diagnosed through a physical examination and blood tests, such as the monospot test or EBV antibody test. Treatment is mainly supportive, including rest, hydration, and over-the-counter medications for pain and fever.


What are the symptoms of lymphoma and how is it diagnosed?

Symptoms of lymphoma can include swollen, painless lymph nodes, unexplained weight loss, night sweats, and fatigue. Diagnosis typically involves a physical exam, blood tests, imaging tests, and sometimes a biopsy of the lymph nodes.


When should I seek immediate medical attention for throat-related symptoms?

You should seek immediate medical attention if you experience worsening difficulty breathing or swallowing, a high fever over 103°F (39.4°C), severe weakness or fatigue, severe or worsening pain, or any other severe or concerning symptoms.


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