[18F] With chronic vaginal discomfort, recurrent UTIs, and systemic symptoms

Patient Description

An 18-year-old female presents with a 3-year history of intermittent vaginal discomfort described as a constant burning sensation, accompanied by yellow, gooey discharge and cloudy urine. Symptoms are exacerbated during urination and sexual activity. She reports frequent urinary tract infections (UTIs) and kidney infections, with occasional episodes of hematuria. Imaging studies revealed one kidney slightly smaller than the other and uterine inflammation, though no structural abnormalities were noted otherwise. Additional symptoms include alternating diarrhea (occurring weekly in large amounts) and constipation (characterized by difficulty passing stools), lower abdominal pain, systemic weakness, chills, and nausea. The abdominal pain is localized to the lower abdomen and is sharp in nature. She also experiences sharp back pain near the kidney region during symptomatic episodes. Symptom relief is achieved temporarily with Azo maximum strength, increased water intake, and masturbation. She has a history of recurrent UTIs confirmed by urine cultures showing significant bacterial growth. No fever has been reported, but chills are frequent during symptomatic episodes. She has also been diagnosed with asthma and has a history of kidney-related issues. No known drug allergies were reported.

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Arora's Assessment

What might be happening

Based on your symptoms and medical history, here are the most likely explanations for what you’re experiencing:

  1. Chronic or Recurrent Urinary Tract Infections (UTIs):

    • Your history of frequent UTIs, cloudy urine, burning sensation, and occasional blood in your urine strongly suggests ongoing or recurrent urinary tract infections. The sharp pain in your back and sides could indicate that the infection sometimes spreads to your kidneys, which is called pyelonephritis (a kidney infection). This would also explain the chills, weakness, and nausea you experience during these episodes.
    • The fact that one of your kidneys is slightly smaller might make you more prone to infections, as this could affect how well your urinary system functions.
  2. Pelvic Inflammatory Disease (PID):

    • The constant vaginal discomfort, yellow and gooey discharge, and history of uterine inflammation seen on imaging could point to Pelvic Inflammatory Disease (PID). This is an infection of the reproductive organs, often caused by bacteria traveling from the vagina to the uterus, fallopian tubes, or ovaries. PID can cause lower abdominal pain, unusual discharge, and even nausea or chills in more severe cases.
    • If left untreated, PID can lead to complications like chronic pelvic pain or fertility issues, so it’s important to address this possibility.
  3. Irritable Bowel Syndrome (IBS):

    • Your alternating diarrhea and constipation, along with abdominal pain, could be related to IBS, a condition that affects how your intestines function. While this may not fully explain your vaginal symptoms, it could be contributing to your abdominal discomfort.
  4. Kidney Stones or Structural Issues:

    • The sharp pain in your back and history of kidney infections could also be related to kidney stones or other structural abnormalities in your urinary tract. While your imaging studies showed normal kidneys apart from the size difference, this is still worth considering.

What you can do

1. Addressing Chronic UTIs and Possible Kidney Infections:

  • See a doctor as soon as possible: Recurrent UTIs and possible kidney infections need medical attention. Your doctor may order a urine culture, blood tests, or imaging (like an ultrasound or CT scan) to check for infections, kidney stones, or other structural issues.
  • Stay hydrated: Drink plenty of water to help flush out bacteria from your urinary tract. Aim for at least 8–10 glasses of water daily.
  • Avoid irritants: Limit caffeine, alcohol, and spicy foods, as these can irritate your bladder.
  • Track your symptoms: Use MDandMe to journal your symptoms, including when they occur, their severity, and any triggers. This can help your doctor identify patterns and make a more accurate diagnosis.

2. Managing Vaginal Discomfort and Possible PID:

  • Seek medical evaluation: A doctor may perform a pelvic exam, vaginal swabs, or an ultrasound to check for infections or inflammation in your reproductive organs. If PID is suspected, antibiotics are typically prescribed.
  • Practice good hygiene: Avoid douching or using scented products in the vaginal area, as these can disrupt the natural balance of bacteria.
  • Wear breathable clothing: Opt for cotton underwear and avoid tight-fitting clothes to reduce irritation.
  • Monitor discharge: Keep track of any changes in the color, texture, or smell of your discharge, as this can provide clues about the underlying issue.

3. Managing Abdominal Pain, Diarrhea, and Constipation:

  • Adjust your diet: Eat a balanced diet rich in fiber (fruits, vegetables, whole grains) to help regulate your bowel movements. Avoid foods that may trigger symptoms, such as greasy or highly processed foods.
  • Stay hydrated: Drinking water can also help with constipation and prevent dehydration from diarrhea.
  • Consider probiotics: Probiotics (found in yogurt or supplements) may help improve gut health and reduce symptoms of IBS.
  • Track bowel habits: Use MDandMe to log your bowel movements, including frequency, consistency, and any associated symptoms.

4. Managing Weakness, Chills, and Nausea:

  • Rest and recover: Your body may be fighting an infection, so prioritize rest and avoid overexertion.
  • Eat small, bland meals: If nausea is severe, stick to foods like crackers, toast, or bananas to avoid upsetting your stomach further.
  • Seek medical care if symptoms worsen: If your weakness, chills, or nausea become severe or are accompanied by fever, seek immediate medical attention, as this could indicate a more serious infection.

What you should look out for

You should seek medical care urgently if you experience any of the following:

  • High fever (above 100.4°F or 38°C) or worsening chills.
  • Severe back or side pain that doesn’t improve with rest.
  • Blood in your urine that becomes more frequent or significant.
  • Fainting, dizziness, or severe weakness.
  • Unusual or foul-smelling vaginal discharge.
  • Persistent nausea or vomiting that prevents you from eating or drinking.

Your symptoms are complex and may involve multiple underlying issues, so it’s important to work closely with a healthcare provider to get a proper diagnosis and treatment plan. In the meantime, tracking your symptoms with MDandMe can help you and your doctor better understand what’s going on. Let me know if you’d like help preparing for your doctor’s visit or have any other questions!

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4 mo ago

People Also Ask


What are the common symptoms of recurrent urinary tract infections (UTIs)?

Common symptoms of recurrent UTIs include a burning sensation during urination, frequent urge to urinate, cloudy or strong-smelling urine, and sometimes blood in the urine.


How can pelvic inflammatory disease (PID) affect reproductive health?

PID can lead to complications such as chronic pelvic pain, infertility, and an increased risk of ectopic pregnancy if left untreated.


What dietary changes can help manage irritable bowel syndrome (IBS)?

Incorporating high-fiber foods, staying hydrated, and avoiding trigger foods like caffeine and spicy dishes can help manage IBS symptoms.


What are the potential causes of a smaller kidney size?

A smaller kidney size can result from congenital conditions, chronic infections, or reduced blood flow to the kidney over time.


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