[18F] Experiencing overwhelming fatigue and sleep disturbances

Patient Description

An 18-year-old female reports overwhelming fatigue, a strong urge to fall asleep, and constant dozing off for about 4-5 days. The fatigue is exacerbated by activities requiring concentration or social interaction and is worst in the morning and late at night. Sleep and caffeine intake alleviate the symptoms somewhat. Additionally, the patient experiences irritability, brain fog, and mood swings. She has been sleeping more heavily and finds it difficult to wake up. Minor sleep paralysis has been noted, but no sudden loss of muscle tone, sleep attacks, hallucinations, or unexpected weakness associated with emotions. The patient denies any recent weight changes, use of recreational drugs, alcohol, or unprescribed medications. There is no known family history of sleep disorders or neurological conditions, no known drug allergies, and no pre-existing conditions or chronic illnesses.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible explanations for your symptoms include:

  • Narcolepsy: A neurological disorder that affects the control of sleep and wakefulness. People with narcolepsy experience excessive daytime sleepiness and intermittent, uncontrollable episodes of falling asleep during the daytime. These sudden sleep attacks may occur during any type of activity at any time of the day. In a typical sleep cycle, we enter the early stages of sleep followed by deeper sleep stages and ultimately (after about 90 minutes) rapid eye movement (REM) sleep. For people suffering from narcolepsy, REM sleep occurs almost immediately in the sleep cycle, as well as periodically during the waking hours. It is in REM sleep that we can experience dreams and muscle paralysis -- which explains the symptoms of waking up feeling unable to move and hallucinations.

    • Treatment for narcolepsy includes medications like stimulants, antidepressants, and sodium oxybate. Also, lifestyle changes such as avoiding caffeine, alcohol, nicotine, and heavy meals, regulating sleep schedules, scheduling daytime naps (10-15 minutes in length), and establishing a normal exercise and meal schedule may also help to reduce symptoms.
  • Chronic Fatigue Syndrome (CFS): A complicated disorder characterized by extreme fatigue that can't be explained by any underlying medical condition. The fatigue may worsen with physical or mental activity but doesn't improve with rest. The cause of chronic fatigue syndrome is still unknown.

    • Treatment can include cognitive-behavioral therapy (CBT), graded exercise therapy (GET), and medication to control pain, nausea, and sleeping problems.
  • Depression: Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest and can interfere with your daily functioning. Symptoms can vary from mild to severe and can include feeling sad or having a depressed mood, loss of interest or pleasure in activities once enjoyed, changes in appetite, trouble sleeping or sleeping too much, loss of energy or increased fatigue, feeling worthless or guilty, difficulty thinking, concentrating or making decisions, and thoughts of death or suicide.

    • Treatment typically includes psychotherapy (talk therapy), medications, or a combination of the two. Lifestyle changes, such as improving sleep habits, increasing physical activity, and eating a healthy diet, can also help manage symptoms.

What you can do

  1. Consult a healthcare provider: They can provide a formal assessment and order relevant tests if necessary. They can also provide appropriate treatments for your symptoms.

  2. Maintain a regular sleep schedule: Try to go to bed and wake up at the same time every day, even on weekends.

  3. Avoid caffeine and alcohol: These substances can interfere with your sleep.

  4. Regular physical activity: Regular physical activity can often help reduce feelings of fatigue.

  5. Stress management: Techniques such as meditation, deep breathing exercises, yoga, or tai chi may help.

What you should look out for

Reasons to seek immediate medical attention:

  • If you feel depressed, have suicidal thoughts, or have thoughts of harming yourself or others.
  • If your symptoms significantly interfere with your daily activities.
  • If your symptoms are causing you distress or concern.

Please remember that this advice is intended to be general in nature, and specific causes may not apply to your situation. Always consult with a healthcare provider for appropriate examination, testing, and care recommendations.

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11 mo ago

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People Also Ask


What are the common symptoms of narcolepsy?

Common symptoms of narcolepsy include excessive daytime sleepiness, sudden loss of muscle tone (cataplexy), sleep paralysis, and hallucinations. People with narcolepsy may also experience disrupted nighttime sleep and automatic behaviors.


How is chronic fatigue syndrome diagnosed?

Chronic fatigue syndrome is diagnosed based on a thorough medical history, physical examination, and ruling out other possible causes of fatigue. There is no specific test for CFS, so diagnosis often involves meeting specific criteria related to the duration and severity of symptoms.


Can depression cause physical symptoms like fatigue?

Yes, depression can cause physical symptoms such as fatigue, changes in appetite, sleep disturbances, and decreased energy levels. These symptoms can significantly impact daily functioning and quality of life.


What lifestyle changes can help manage excessive daytime sleepiness?

Lifestyle changes that can help manage excessive daytime sleepiness include maintaining a regular sleep schedule, avoiding caffeine and alcohol, engaging in regular physical activity, and practicing stress management techniques like meditation or yoga.


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