[60F] Experiencing severe foot pain and cold sensation with discoloration

Patient Description

A 60-year-old female presents with significant foot pain and a persistent cold sensation in her toes for the past two weeks. Despite feeling cold, the toes are warm to touch and exhibit a reddish-purple discoloration. The pain extends up the leg and is accompanied by numbness and tingling. The foot feels hard to touch. The patient has a history of high blood pressure, managed with Lisinopril (20 mg daily), and recent blood work indicates prediabetes. She smokes half a pack of cigarettes per day and does not consume alcohol. Other medications include Gabapentin (800 mg, three times a day), Prozac (40 mg, once a day), and Risperidone (4 mg, at bedtime). She has been on these medications for several years. The patient's father had a history of strokes. No chest pain or shortness of breath reported.

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Arora's Assessment

What might be happening

Based on the symptoms and history you've provided, here are some possible explanations for your condition:

Peripheral Artery Disease (PAD)

  • Rationale: PAD occurs when the arteries that supply blood to your limbs become narrowed or blocked. Symptoms can include pain, numbness, and a cold sensation in the affected limb, even if it feels warm to the touch. The reddish-purple color and hard texture of your foot, along with the pain extending up your leg, are also consistent with PAD.
  • Typical Treatments/Testing: Diagnosis often involves a physical exam, blood tests, and imaging studies like an ultrasound or angiography. Treatment may include lifestyle changes, medications to improve blood flow, and possibly surgical interventions.

Diabetic Neuropathy

  • Rationale: Given your prediabetic status, diabetic neuropathy is a possibility. This condition involves nerve damage due to high blood sugar levels and can cause pain, numbness, and a cold sensation in the feet and legs.
  • Typical Treatments/Testing: Diagnosis usually involves a physical exam, blood tests, and nerve function tests. Treatment focuses on managing blood sugar levels, pain relief, and lifestyle changes.

Deep Vein Thrombosis (DVT)

  • Rationale: DVT is a blood clot that forms in a deep vein, usually in the legs. Symptoms can include swelling, pain, and a change in color of the affected limb. The hard texture of your foot and the pain extending up your leg could be indicative of DVT.
  • Typical Treatments/Testing: Diagnosis often involves a physical exam, blood tests, and imaging studies like an ultrasound. Treatment typically includes blood thinners and sometimes surgical intervention.

What you can do

Peripheral Artery Disease (PAD)

  • Seek Medical Attention: It's crucial to see a healthcare provider as soon as possible for a proper diagnosis and treatment plan.
  • Lifestyle Changes: Quit smoking, as it can worsen PAD. Engage in regular physical activity and maintain a healthy diet.
  • Medication: Your doctor may prescribe medications to improve blood flow and manage symptoms.

Diabetic Neuropathy

  • Blood Sugar Management: Work with your healthcare provider to manage your blood sugar levels effectively.
  • Pain Management: Over-the-counter pain relievers may help, but consult your doctor for specific recommendations.
  • Foot Care: Regularly check your feet for any sores or injuries and keep them clean and dry.

Deep Vein Thrombosis (DVT)

  • Seek Immediate Medical Attention: DVT can be life-threatening if the clot travels to your lungs, causing a pulmonary embolism.
  • Medication: Your doctor may prescribe blood thinners to prevent the clot from growing.
  • Compression Stockings: These can help reduce swelling and improve blood flow.

What you should look out for

Given the severity of your symptoms and the potential for serious underlying conditions, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Sudden Increase in Pain or Swelling: This could indicate a worsening of your condition.
  • Shortness of Breath or Chest Pain: These could be signs of a pulmonary embolism, which is a medical emergency.
  • Changes in Skin Color or Temperature: If your foot becomes significantly colder or changes color, seek immediate medical attention.

Remember, while I can provide information and suggestions, it's essential to consult a healthcare professional for a formal diagnosis and treatment plan. You can also use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

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6 mo ago

People Also Ask


What are the common symptoms of Peripheral Artery Disease (PAD)?

Common symptoms of Peripheral Artery Disease (PAD) include leg pain or cramping during physical activities, numbness or weakness in the legs, coldness in the lower leg or foot, sores or wounds on toes, feet, or legs that won't heal, and a change in the color of the legs.


How can prediabetes lead to diabetic neuropathy?

Prediabetes can lead to diabetic neuropathy because elevated blood sugar levels over time can damage nerves throughout the body, particularly in the legs and feet. This nerve damage can cause symptoms such as pain, tingling, and numbness.


What are the risks associated with Deep Vein Thrombosis (DVT)?

Deep Vein Thrombosis (DVT) can be dangerous because the blood clot in a deep vein can break loose and travel to the lungs, causing a pulmonary embolism, which is a life-threatening condition. Other risks include chronic pain and swelling in the affected limb.


How does smoking affect conditions like PAD and diabetic neuropathy?

Smoking can worsen conditions like PAD and diabetic neuropathy because it damages blood vessels, reduces blood flow, and increases the risk of blood clots. This can exacerbate symptoms and lead to more severe complications.


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