[49F] Evaluation of missed periods, PCOS, leukocytosis, and weight gain

Patient Description

A 49-year-old female presents with concerns about missed periods, diagnosed PCOS, persistent leukocytosis, and recent weight gain. Over the last 8 months, she has gained 22 pounds, which she attributes to increased consumption of regular soda, from 2 to 4 cans daily. Her periods stopped 3 months ago, and she has a long-standing history of irregular periods due to PCOS. Additionally, she reports always having slightly elevated white blood cell counts, around 13,000, for the past 10 years. She is currently managing degenerative disc disease with a history of a C5-C7 plate and laminectomy. Her current medications include Venlafaxine, Topiramate, Adderall, Oxycodone, Vitamin D, and Ibuprofen.

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Arora's Assessment

What might be happening

Based on the information you provided, the following conditions could be contributing to your symptoms:

  • Polycystic Ovary Syndrome (PCOS): This is a hormonal disorder common among women of reproductive age. Women with PCOS may have infrequent or prolonged menstrual periods or excess male hormone (androgen) levels. This can result in weight gain, acne, and excessive hair growth (hirsutism), all of which you have reported.

    • Treatment for PCOS often involves lifestyle changes like a healthy diet and regular exercise. Medications may also be prescribed to manage individual symptoms like menstrual irregularities and hirsutism.
  • Menopause: You mentioned that you are 49 years old and your periods have stopped. This could be a sign of menopause, which typically occurs in women between 45 and 55 years of age. Symptoms can include hot flashes, night sweats, mood changes, and weight gain.

    • Treatment for menopause symptoms can include hormone replacement therapy (HRT), as well as lifestyle changes and over-the-counter remedies.
  • Leukocytosis: This is a condition characterized by an increased number of white blood cells. It is often a response to an infection or inflammation, but can also be caused by certain medications, stress, or underlying conditions like leukemia.

    • Treatment for leukocytosis depends on the underlying cause. It's important to follow up with your healthcare provider to monitor this condition.

Please note that this is not a definitive diagnosis, and it's important to consult with a healthcare provider for a formal assessment.

What you can do

  1. Consider reducing your soda intake: Regular soda is high in sugar and calories, which can contribute to weight gain. Try replacing soda with healthier alternatives like water, unsweetened tea, or flavored sparkling water.

  2. Maintain a healthy diet and regular exercise: This can help manage weight gain and improve overall health. Aim for a balanced diet rich in fruits, vegetables, lean proteins, and whole grains. Regular physical activity can also help manage weight and improve mood.

  3. Consult with a healthcare provider: It's important to discuss your symptoms with a healthcare provider who can provide a formal assessment and recommend appropriate treatment options.

What you should look out for

  • If your symptoms worsen or if you develop new symptoms, it's important to seek medical attention.
  • If you experience severe abdominal pain, heavy vaginal bleeding, or severe mood changes, seek immediate medical attention.
  • If your leukocytosis worsens or if you develop symptoms like fever, chills, or unexplained weight loss, consult with a healthcare provider as soon as possible.

Remember, it's important to consult with a healthcare provider for a formal diagnosis and treatment. This information is intended to be educational and should not be used as a substitute for professional medical advice.

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6 mo ago


People Also Ask


What are the common symptoms of PCOS and how can they be managed?

Common symptoms of PCOS include irregular menstrual cycles, weight gain, acne, and excessive hair growth. Management often involves lifestyle changes such as a healthy diet and regular exercise, and medications may be prescribed to address specific symptoms like menstrual irregularities.


How can menopause affect menstrual cycles and what are the common symptoms?

Menopause can lead to the cessation of menstrual cycles and is typically accompanied by symptoms such as hot flashes, night sweats, mood changes, and weight gain. Treatment options include hormone replacement therapy and lifestyle changes to manage symptoms.


What could be the causes of persistent leukocytosis and how is it treated?

Persistent leukocytosis can be caused by infections, inflammation, stress, certain medications, or underlying conditions like leukemia. Treatment depends on the underlying cause, and it is important to monitor the condition with a healthcare provider.


How does excessive soda consumption contribute to weight gain?

Excessive soda consumption contributes to weight gain due to its high sugar and calorie content. Reducing soda intake and replacing it with healthier alternatives like water or unsweetened beverages can help manage weight.

1 Comments


Anonymous#19741

6 mo ago

In my late 20s, I experienced a significant and sudden weight gain, going from 130 lbs to 180 lbs within 6 months to a year. Lat year at age of 29, I received a diagnosis of PCOS Currently, I weigh around 207 lbs. Over the past 8 weeks, I have made significant changes to my diet, but I have barely lost any weight. Recently, I indulged a bit during holiday parties, and now I feel awful because my weight has returned to its starting point, despite my efforts over the past 8 weeks. If you know anythign that has helped you please let me know because i am so frickin tired of this condition and feeling and looking awful

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