[48F] With nausea, fever, and other systemic symptoms

Patient Description

A 48-year-old female has been experiencing constant nausea, weakness, fever (100.7°F), chills, and a loss of appetite for the past four days. The nausea came on suddenly and is not relieved by any specific activities or foods. She also reports a moderate headache located at the back of her head but denies any cough, muscle aches, or sore throat. Her medical history includes asthma, adrenal insufficiency, and GERD (diagnosed in 2000). She is currently taking hydrocortisone (15 mg in the morning and 5 mg in the afternoon), Flovent (2 puffs twice a day), Omeprazole (40 mg once a day), Gabapentin (300 mg three times a day), Fluoxetine (20 mg once a day), Iron (325 mg once a day), and Vitamin D3 (50 mcg once a day). She has not missed any doses of her hydrocortisone. She does not use tobacco, alcohol, or recreational drugs and has not been exposed to anyone with similar symptoms recently. She has no known drug allergies and has not experienced any side effects from her current medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described—nausea, fever, sweats, chills, weakness, and loss of appetite—there are several potential explanations. Given your medical history of asthma and adrenal insufficiency, it's important to consider both common and serious conditions:

  1. Infection: Your symptoms could be due to a viral or bacterial infection. Common infections like the flu or a gastrointestinal infection can cause nausea, fever, chills, and weakness. However, given the duration and severity of your symptoms, a more serious infection such as a urinary tract infection (UTI) or even sepsis (a severe infection that spreads throughout the body) could be possible.

  2. Adrenal Insufficiency Crisis: Given your history of adrenal insufficiency, it's crucial to consider the possibility of an adrenal crisis, which can be life-threatening. Symptoms of an adrenal crisis include severe weakness, nausea, vomiting, fever, and low blood pressure.

  3. Medication Side Effects: Although you mentioned not experiencing side effects from your medications, it's still possible that a combination of medications or a new interaction could be contributing to your symptoms.

  4. Other Conditions: Conditions like dehydration, electrolyte imbalances, or even more serious issues like a heart condition could also present with similar symptoms.

What you can do

  1. Seek Immediate Medical Attention: Given the severity and duration of your symptoms, and especially considering your history of adrenal insufficiency, it is crucial to seek immediate medical attention. You should go to the nearest emergency room or urgent care center. If you feel too weak to drive, please call 911 or have someone take you to the hospital.

  2. Monitor Symptoms: Keep track of any new symptoms or changes in your current symptoms. This information will be helpful for healthcare providers.

  3. Stay Hydrated: Drink plenty of fluids to stay hydrated, especially if you are experiencing fever and sweats.

  4. Medication Management: Ensure you continue taking your prescribed medications as directed. If you suspect an adrenal crisis, you may need to take an emergency dose of hydrocortisone as prescribed by your doctor.

  5. Rest: Get plenty of rest to help your body fight off any potential infection.

Remember, while I can provide information based on your symptoms, I am not a doctor. It is essential to seek care from a real health professional to receive a formal diagnosis and appropriate treatment. If your symptoms worsen or you feel that you are in immediate danger, please call 911.

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3 mo ago


People Also Ask


What are the symptoms of an adrenal insufficiency crisis?

Symptoms of an adrenal insufficiency crisis include severe weakness, nausea, vomiting, fever, low blood pressure, and sometimes confusion or loss of consciousness. It is a medical emergency and requires immediate treatment.


Can a viral or bacterial infection cause nausea and fever?

Yes, both viral and bacterial infections can cause symptoms like nausea and fever. Common infections such as the flu or gastrointestinal infections often present with these symptoms.


How can medication interactions contribute to symptoms like nausea and weakness?

Medication interactions can lead to side effects such as nausea and weakness by altering the way drugs are metabolized or by causing additive effects. It's important to review all medications with a healthcare provider to identify potential interactions.


What steps should be taken if experiencing severe symptoms with a history of adrenal insufficiency?

If experiencing severe symptoms with a history of adrenal insufficiency, it is crucial to seek immediate medical attention. This may involve going to the emergency room, taking an emergency dose of hydrocortisone if prescribed, and ensuring proper hydration and rest.

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