[46F] With widespread itchy rash and systemic symptoms

Patient Description

A 46-year-old female reports experiencing small, itchy red bumps all over her body for the past three days. The rash appeared gradually, with individual bumps swelling and blistering slightly when scratched. The patient notes a slight fever, fatigue, and body aches accompanying the rash. Symptoms seem to worsen when indoors. The patient spends significant time outdoors and may have been exposed to potential allergens or irritants. No recent changes in skincare products, detergents, or medications are reported. The patient has attempted using fingernail polish and bleach on the rash without relief. There is no history of allergies or previous skin conditions. The patient is currently taking biotin (10,000 mcg) and a collagen supplement with vitamin C and biotin (2,500 mcg) once daily. No other medications or supplements are reported.

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Arora's Assessment

What might be happening

Based on your symptoms, here are some possible explanations:

  • Contact Dermatitis: This is a skin reaction to an irritant or allergen. Given your outdoor activities, you might have come into contact with a plant or substance causing the rash. It typically causes red, itchy bumps and can blister if scratched.

    • Treatment involves identifying and avoiding the irritant. Over-the-counter creams like hydrocortisone can help reduce itching and inflammation.
  • Viral Exanthem: A viral infection can cause a widespread rash accompanied by fever and body aches. This is common with viral illnesses.

    • Treatment usually involves rest, hydration, and over-the-counter medications to manage symptoms.
  • Allergic Reaction: Although you haven't changed products, an allergic reaction to something in your environment or diet could cause these symptoms.

    • Antihistamines like Benadryl can help alleviate itching.

What you can do

  1. Avoid Scratching: Try to keep from scratching the rash to prevent further irritation or infection.
  2. Cool Compresses: Apply cool, damp cloths to the affected areas to soothe itching.
  3. Over-the-Counter Creams: Use anti-itch creams or calamine lotion to help with the itching.
  4. Track Symptoms: Use MDandMe to journal your symptoms, track any changes, and share this information with your healthcare provider.

What you should look out for

Seek medical attention if:

  • The rash spreads rapidly or becomes painful.
  • You develop a high fever or severe fatigue.
  • You notice signs of infection, such as increased redness, warmth, or pus.

Remember, it's important to consult a healthcare professional for a formal diagnosis and treatment plan.

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2 mo ago


People Also Ask


What are common causes of contact dermatitis?

Common causes of contact dermatitis include exposure to plants like poison ivy, chemicals, soaps, and certain metals. It occurs when the skin comes into contact with an irritant or allergen.


How can I differentiate between a viral exanthem and an allergic reaction?

A viral exanthem often comes with systemic symptoms like fever and body aches, while an allergic reaction might be more localized and primarily involve itching. A healthcare provider can help differentiate between the two based on symptoms and history.


What are some effective over-the-counter treatments for itchy rashes?

Effective over-the-counter treatments for itchy rashes include hydrocortisone cream, calamine lotion, and antihistamines like Benadryl. These can help reduce itching and inflammation.


When should I seek medical attention for a rash?

You should seek medical attention if the rash spreads rapidly, becomes painful, if you develop a high fever, severe fatigue, or if there are signs of infection such as increased redness, warmth, or pus.


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