[46F] Recurrent paralysis attacks with severe migraines and neurological symptoms

What might be happening

Based on the information you've provided, it seems like your symptoms could be related to multiple underlying issues. Here are some possibilities:

1. Transverse Myelitis

• Rationale: Your symptoms of sudden onset paralysis, severe spine pain, and tingling sensations are consistent with transverse myelitis, which involves inflammation of the spinal cord. This condition can be triggered by infections, which aligns with your history of upper respiratory infections preceding your attacks.
• Typical Treatments/Testing: Diagnosis often involves MRI scans of the spine, lumbar puncture, and blood tests. Treatment may include corticosteroids to reduce inflammation, plasma exchange therapy, and physical therapy for rehabilitation.

2. Polyradiculoneuropathy

• Rationale: This condition involves inflammation of multiple nerve roots and can cause symptoms like paralysis, tingling, and pain. Your high SED rate and C-reactive proteins suggest an inflammatory process, which fits with this diagnosis.
• Typical Treatments/Testing: Diagnosis may involve nerve conduction studies, electromyography (EMG), and blood tests. Treatment often includes immunosuppressive medications, intravenous immunoglobulin (IVIG), and physical therapy.

3. Autoimmune Disorder

• Rationale: Given your family history of autoimmune diseases and your positive ANA test, an autoimmune disorder could be contributing to your symptoms. Conditions like lupus or multiple sclerosis could present with neurological symptoms and inflammation.
• Typical Treatments/Testing: Diagnosis may involve a combination of blood tests, imaging studies, and sometimes a biopsy. Treatment often includes immunosuppressive medications, corticosteroids, and symptom management strategies.

What you can do

Immediate Steps

1. Seek Medical Attention: Given the severity and recurrence of your symptoms, it's crucial to consult with a neurologist or a specialist in autoimmune diseases. They can perform the necessary tests to confirm a diagnosis and recommend appropriate treatment.
2. Emergency Care: If you experience another attack, especially with severe symptoms like paralysis or intense pain, seek emergency medical care immediately.

Managing Symptoms at Home

1. Pain Management:
   • Use over-the-counter pain relievers like acetaminophen or ibuprofen, but consult your doctor first.
   • Apply heat or cold packs to your spine to help alleviate pain.
2. Physical Therapy:
   • Continue working with your physical therapist to regain movement and strength in your affected limbs.
   • Gentle stretching and strengthening exercises can help improve mobility and reduce pain.
3. Fatigue Management:
   • Ensure you get adequate rest and avoid overexertion.
   • Maintain a balanced diet and stay hydrated to support your overall health.
4. Symptom Tracking:
   • Use MDandMe to journal your symptoms, track your progress, and get insights. This can help you and your healthcare provider understand your condition better and adjust your treatment plan as needed.

What you should look out for

Given the complexity and severity of your symptoms, it's important to monitor for any changes or worsening of your condition. Seek medical care immediately if you experience:

• New or worsening paralysis or weakness
• Severe or unmanageable pain
• Difficulty breathing or swallowing
• Loss of bladder or bowel control
• High fever or signs of infection

Remember, while I can provide information and suggestions, it's essential to consult with real healthcare professionals to receive a formal diagnosis and appropriate treatment. If you have more questions or need further assistance, feel free to continue the conversation.