[45F] Experiencing muscle fatigue and palpitations

Patient Description

A 45-year-old female reports experiencing muscle fatigue in her arms and legs for several months, relieved by rest. She also experiences heart palpitations and a dull, tired ache rated 7/10 in severity, especially after activities such as walking up stairs or lifting arms. Shortness of breath occurs during and after activity, accompanied by dizziness or lightheadedness. No swelling in legs or feet, chest pain, headaches, or changes in vision noted. Current medications include Nifedipine ER 60mg once daily, Labetalol 200mg twice daily, Bupropion XL 300mg once daily, Adderall 20mg twice daily, Percocet 10/325mg every 6 hours as needed, Gabapentin 300mg twice daily, Escitalopram 10mg once daily, and Omeprazole 20mg once daily. No recent changes in medication dosages. Family history includes mother deceased from a heart attack. Medical history includes high blood pressure, anemia, tachycardia, chronic pain, fibromyalgia, ADHD, and depression, diagnosed approximately five years ago. No known drug allergies.

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Arora's Assessment

What might be happening

Your symptoms of muscle fatigue, palpitations, and achiness in your arms and legs could be related to several conditions:

  1. Fibromyalgia: This condition often causes widespread muscle pain and fatigue. It can also lead to symptoms like dizziness and palpitations.

  2. Anemia: Low red blood cell levels can cause fatigue, dizziness, and palpitations, especially during physical activity.

  3. Medication Side Effects: Some of your medications, like Adderall and Percocet, can cause palpitations and fatigue as side effects.

  4. Cardiovascular Issues: Given your family history and symptoms, it's important to rule out heart-related issues, especially since you experience shortness of breath and palpitations.

Typical treatments or tests might include blood tests to check for anemia, a review of your medications, and possibly a heart evaluation.

What you can do

For Muscle Fatigue and Achiness:

  • Rest: Continue to rest as needed and avoid overexertion.
  • Gentle Exercise: Engage in low-impact activities like walking or swimming to maintain muscle strength without overstraining.
  • Pain Management: Use over-the-counter pain relief if needed, but consult your doctor about your current medications.

For Palpitations and Dizziness:

  • Monitor Symptoms: Keep track of when these symptoms occur and any potential triggers.
  • Stay Hydrated: Ensure you are drinking enough fluids, as dehydration can worsen these symptoms.
  • Consult Your Doctor: Discuss these symptoms with your healthcare provider, especially given your family history of heart disease.

Consider using MDandMe to journal your symptoms, track progress, and share insights with your healthcare provider.

What you should look out for

Seek medical attention if you experience:

  • Severe or worsening shortness of breath
  • Chest pain or pressure
  • Fainting or severe dizziness

These could be signs of a more serious condition that requires immediate attention. Always consult with a healthcare professional for a formal diagnosis and treatment plan.

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3 mo ago

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People Also Ask


What could be causing my muscle fatigue and palpitations?

Muscle fatigue and palpitations could be due to fibromyalgia, anemia, medication side effects, or cardiovascular issues. It's important to consult with your doctor for a proper diagnosis.


How can I manage dizziness and shortness of breath during activities?

To manage dizziness and shortness of breath, monitor your symptoms, stay hydrated, and avoid overexertion. Gentle exercise and rest can also help. Discuss these symptoms with your healthcare provider.


Are my medications contributing to my symptoms?

Yes, medications like Adderall and Percocet can cause palpitations and fatigue. It's important to review your medications with your doctor to determine if they are contributing to your symptoms.


When should I seek medical attention for my symptoms?

Seek medical attention if you experience severe or worsening shortness of breath, chest pain, or fainting. These could be signs of a more serious condition.


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