[43M] With sudden swelling under left armpit and groin

Patient Description

A 43-year-old male reports sudden onset of soft swelling under the left armpit and inside the left leg/groin, persisting for about a week. The swelling has increased in size but is not associated with redness, warmth, pain, or tenderness. The patient denies recent infections or injuries. Accompanying symptoms include night sweats and fatigue, but no fever, unexplained weight loss, or appetite changes. The patient has a history of gout, high blood pressure, and high cholesterol, diagnosed two years ago, and is not currently on any medications. Substance use includes daily tobacco and methamphetamine, and alcohol consumption a couple of times a week. No recent travel or known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your symptoms:

  • Lymphadenopathy: Swelling in the armpit and groin could be due to enlarged lymph nodes, which can occur due to infections, inflammation, or other conditions. Since there's no redness or pain, it might not be an acute infection, but it's still important to monitor.

  • Lipoma: These are soft, benign lumps of fatty tissue that can grow under the skin. They are usually painless and can increase in size over time.

  • Hernia: In the groin area, a hernia could cause swelling. This occurs when tissue pushes through a weak spot in the abdominal muscles. It’s usually more noticeable when standing or straining.

  • Substance Use Effects: Daily use of methamphetamine and tobacco can have various effects on your body, including potential impacts on your immune system and lymphatic system.

Typical treatments or tests might include a physical examination, imaging tests like an ultrasound, or blood tests to rule out infections or other conditions.

What you can do

  • Consult a Healthcare Provider: It's important to see a doctor for a proper evaluation. They can determine the cause of the swelling and recommend appropriate tests or treatments.

  • Monitor Symptoms: Keep track of any changes in the size or feel of the swelling, and note any new symptoms.

  • Lifestyle Considerations: Reducing or quitting tobacco and methamphetamine use can improve overall health and potentially reduce symptoms.

  • Symptom Tracking: Use MDandMe to journal your symptoms, track any changes, and share this information with your healthcare provider.

What you should look out for

Seek medical attention if you experience:

  • Rapid increase in swelling size
  • Pain or tenderness in the swollen areas
  • Fever or chills
  • Any new or worsening symptoms

Remember, this information is not a substitute for professional medical advice. Please consult a healthcare provider for a formal diagnosis and treatment plan.

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4 mo ago

People Also Ask


What could cause sudden swelling under the armpit and in the groin area?

Sudden swelling in these areas could be due to enlarged lymph nodes, lipomas, or hernias. Lymphadenopathy, for instance, can occur due to infections or inflammation, while lipomas are benign fatty lumps. Hernias involve tissue pushing through a weak spot in the muscles.


Are night sweats and fatigue related to the swelling?

Night sweats and fatigue can be associated with various conditions, including infections or systemic issues that might also cause lymph node swelling. It's important to consider these symptoms together and consult a healthcare provider for a comprehensive evaluation.


How does substance use like methamphetamine and tobacco affect lymph nodes?

Substance use, particularly methamphetamine and tobacco, can impact the immune and lymphatic systems, potentially leading to changes in lymph node size or function. These substances can also contribute to overall health issues that might indirectly affect lymph nodes.


What are the potential risks if the swelling increases or becomes painful?

If the swelling increases rapidly or becomes painful, it could indicate an underlying issue that requires medical attention, such as an infection or a more serious condition. It's important to monitor these changes and seek medical advice promptly.


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