[43F] With sore joints, swollen lymph node, and other symptoms

What might be happening

Based on the symptoms and history you've provided, here are some possible explanations for your condition:

1. Infection or Inflammatory Condition

• Swollen Lymph Node, Diarrhea, Nausea, Night Sweats, and Fatigue: These symptoms could indicate an infection or an inflammatory condition. Given your recent increase in Humira dosage, it's possible that your immune system might be more susceptible to infections. Humira is an immunosuppressant, which can increase the risk of infections.
• Typical Treatments and Testing: Your doctor might order blood tests, imaging studies, or a biopsy of the swollen lymph node to determine the cause. Antibiotics or antiviral medications might be prescribed if an infection is identified.

2. Autoimmune or Rheumatologic Condition

• Sore Joints and Muscles: These symptoms, along with your family history of psoriasis, could suggest an autoimmune or rheumatologic condition such as psoriatic arthritis or another type of inflammatory arthritis.
• Typical Treatments and Testing: Your doctor might recommend blood tests to check for markers of inflammation and autoimmune activity. Imaging studies like X-rays or MRIs might also be used. Treatment could include anti-inflammatory medications, physical therapy, or adjustments to your current medications.

3. Medication Side Effects

• Diarrhea, Nausea, and Fatigue: These could be side effects of your medications, particularly Metformin and Humira. It's important to discuss these symptoms with your doctor to see if any adjustments are needed.
• Typical Treatments and Testing: Your doctor might review your medication regimen and make adjustments as needed. They might also recommend supportive care for symptom relief.

What you can do

Sore Joints and Muscles

• See a Doctor: Given the severity and sudden onset of your hip pain, it's important to consult a healthcare provider. They might recommend imaging studies or refer you to a specialist.
• At Home: Continue taking Advil as needed, but do not exceed the recommended dosage. Rest and avoid activities that exacerbate the pain. Applying ice or heat might also provide relief.

Swollen Lymph Node, Diarrhea, Nausea, Night Sweats, and Fatigue

• See a Doctor: These symptoms could indicate an infection or another serious condition, especially given your use of Humira. It's important to get a thorough evaluation, which might include blood tests and imaging studies.
• At Home: Stay hydrated, especially if you have diarrhea. Eat small, bland meals to help with nausea. Keep a record of your symptoms using the MDandMe journal to track any changes and share this information with your healthcare provider.

What you should look out for

Given the complexity and severity of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

• Fever or Chills: These could indicate an infection that needs prompt treatment.
• Severe or Worsening Pain: If your hip pain becomes unbearable or spreads to other areas.
• New or Worsening Symptoms: Such as shortness of breath, chest pain, or significant changes in bowel movements.
• Signs of Severe Infection: Such as high fever, severe fatigue, or confusion.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment. If you have more questions or need further assistance, feel free to continue the conversation.