[41F] With numbness, tingling, and swelling in extremities

Patient Description

A 41-year-old female presents with numbness and tingling in her hands, fingers, feet, and toes for the past 3 to 4 months. The numbness is generalized and constant, while the tingling feels like pins and needles with sharp shooting pain. Activities such as raising her hands to perform tasks like driving or washing her hair exacerbate the symptoms. Additionally, she experiences sudden severe headaches, changes in vision, muscle weakness, difficulty with coordination, significant weight gain, and swelling in her fingers, particularly when driving. Her medical history includes hydrocephalus with a shunt placed in August 2022, high blood pressure, hypothyroidism, and anxiety, all diagnosed at age 18. She is allergic to contrast dye. Current medications are Levothyroxine 25 mcg, Lisinopril 5 mg, Keppra 2000 mg, Loratadine 10 mg, and Citalopram 10 mg, all taken once daily. She also takes Acetaminophen 200 mg every 6 hours and Benadryl 10 mg once daily.

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Arora's Assessment

What might be happening

Based on the information you have provided, several potential diagnoses could explain your symptoms:

  • Peripheral Neuropathy: This condition involves damage to the peripheral nerves and can cause numbness, tingling, and pain in the hands and feet. It can be caused by diabetes, hypothyroidism, and other metabolic disorders.

    • Treatment: Managing the underlying condition (e.g., controlling blood sugar in diabetes, adjusting thyroid medication) and medications to relieve nerve pain.
  • Carpal Tunnel Syndrome: This occurs when the median nerve is compressed as it travels through the wrist. It can cause numbness, tingling, and pain in the fingers and hand, especially when performing activities that involve wrist movement.

    • Treatment: Wrist splints, anti-inflammatory medications, and possibly surgery if symptoms are severe.
  • Cervical Radiculopathy: This condition involves compression or irritation of the nerves in the neck, which can cause numbness, tingling, and pain that radiates down the arms and hands.

    • Treatment: Physical therapy, medications to reduce pain and inflammation, and sometimes surgery.
  • Multiple Sclerosis (MS): A chronic condition that affects the central nervous system, leading to symptoms like numbness, tingling, muscle weakness, and coordination problems.

    • Treatment: Disease-modifying therapies, physical therapy, and medications to manage symptoms.
  • Vitamin Deficiencies: Deficiencies in vitamins such as B12 can lead to neuropathy and symptoms like numbness and tingling.

    • Treatment: Vitamin supplementation and dietary changes.

What you can do

While you should consult a healthcare professional for a formal diagnosis and treatment plan, here are some steps you can take in the meantime:

  1. Manage Underlying Conditions: Ensure that your hypothyroidism and high blood pressure are well-controlled with your current medications. Regular follow-ups with your healthcare provider are essential.
  2. Ergonomic Adjustments: Make ergonomic adjustments to your workspace and daily activities to reduce strain on your hands and wrists. Use wrist splints if recommended.
  3. Healthy Lifestyle: Maintain a balanced diet rich in vitamins and minerals, and consider taking a multivitamin if recommended by your doctor.
  4. Physical Therapy: Engage in exercises and stretches that can help alleviate nerve compression and improve circulation.
  5. Pain Management: Over-the-counter pain relievers like acetaminophen can help manage pain, but consult your doctor for long-term pain management strategies.

What you should look out for

Seek medical attention if you experience any of the following:

  • Worsening Symptoms: If your numbness, tingling, or pain worsens or becomes more frequent.
  • New Symptoms: If you develop new symptoms such as severe headaches, vision changes, or significant muscle weakness.
  • Severe Swelling: If the swelling in your fingers or other areas becomes severe or persistent.
  • Difficulty Performing Daily Activities: If your symptoms interfere with your ability to perform daily activities or affect your quality of life.

Remember, while this information can help guide you, it is essential to consult a healthcare professional for a formal diagnosis and appropriate treatment.

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6 mo ago

People Also Ask


What are the common causes of numbness and tingling in the hands and feet?

Common causes of numbness and tingling in the hands and feet include peripheral neuropathy, carpal tunnel syndrome, cervical radiculopathy, vitamin deficiencies, and conditions like multiple sclerosis. These symptoms can also be related to metabolic disorders such as diabetes and hypothyroidism.


How can hypothyroidism contribute to symptoms like numbness and tingling?

Hypothyroidism can lead to peripheral neuropathy, which causes numbness and tingling. This occurs because low thyroid hormone levels can affect nerve health and function. Proper management of hypothyroidism with medication can help alleviate these symptoms.


What lifestyle changes can help manage symptoms of peripheral neuropathy?

Lifestyle changes that can help manage peripheral neuropathy include maintaining a balanced diet rich in vitamins and minerals, engaging in regular physical activity, avoiding alcohol, and managing underlying conditions like diabetes or hypothyroidism. Ergonomic adjustments and physical therapy can also be beneficial.


When should I seek medical attention for symptoms like numbness and tingling?

You should seek medical attention if your numbness and tingling worsen, if you experience new symptoms such as severe headaches or vision changes, if swelling becomes severe, or if your symptoms interfere with daily activities and affect your quality of life.


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