[38M] Experiencing sudden knee pain with swelling and redness

Patient Description

A 38-year-old male presents with sudden onset of pain in the front of the knee, persisting for four days. The pain is severe, rated 7 out of 10, and worsens with any activity. The patient reports associated swelling and redness but denies any recent injuries, infections, fevers, or chills. There is no recent change in physical activity. The patient has tried ibuprofen and muscle relaxers with minimal relief. Medical history includes a chronic cough, multiple back and neck surgeries, and fluid around the heart. The patient is unsure about any family history due to being adopted. No known allergies reported. The patient is currently taking ibuprofen and has used muscle relaxers on occasion.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your knee pain:

  • Patellofemoral Pain Syndrome (Runner's Knee): This condition is characterized by pain at the front of the knee, around the kneecap. It can occur without a specific injury and is often due to overuse, muscle imbalances, or improper movement patterns. Swelling and a sensation of heat can accompany the pain.

    • Treatment typically involves rest, ice, compression, and elevation (RICE), along with physical therapy exercises to strengthen the muscles around the knee.
  • Prepatellar Bursitis: This is inflammation of the bursa (a small fluid-filled sac) in front of the kneecap, often caused by prolonged kneeling or a direct blow to the knee. It can cause swelling, redness, and warmth.

    • Treatment may include avoiding activities that worsen the symptoms, using anti-inflammatory medications, and in some cases, aspiration of the bursa fluid by a healthcare professional.
  • Gout or Pseudogout: These are types of arthritis caused by the accumulation of crystals in the joint, leading to sudden and severe pain, swelling, and redness. Although you mentioned no known history of gout, it can sometimes present without prior diagnosis.

    • Treatment involves medications to reduce inflammation and pain, and lifestyle changes to manage uric acid levels.

What you can do

While it's important to consult a healthcare professional for a formal diagnosis and treatment plan, here are some steps you can take to manage your symptoms:

  1. Rest and Protect Your Knee: Avoid activities that worsen the pain. Consider using a knee brace or support to stabilize the joint.
  2. Apply Ice: Use an ice pack on your knee for 15-20 minutes every few hours to reduce swelling and pain.
  3. Elevate Your Leg: When resting, keep your leg elevated above the level of your heart to help reduce swelling.
  4. Over-the-Counter Pain Relief: Continue using ibuprofen as directed to help manage pain and inflammation, unless advised otherwise by a healthcare professional.
  5. Track Your Symptoms: Use the MDandMe app to journal your symptoms, track any changes, and share this information with your healthcare provider for a more comprehensive assessment.

What you should look out for

Seek medical attention if you experience any of the following:

  • Increased swelling, redness, or warmth in the knee
  • Fever or chills, which could indicate an infection
  • Inability to bear weight on the affected leg
  • Severe pain that does not improve with rest and medication

Remember, while these suggestions can help manage your symptoms, it's crucial to consult a healthcare professional for a proper diagnosis and treatment plan.

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People Also Ask


What are the common causes of sudden knee pain without injury?

Common causes of sudden knee pain without injury include patellofemoral pain syndrome, prepatellar bursitis, and arthritis conditions like gout or pseudogout. These conditions can arise from overuse, inflammation, or crystal accumulation in the joint.


How can I differentiate between patellofemoral pain syndrome and prepatellar bursitis?

Patellofemoral pain syndrome typically presents as pain around the kneecap, often worsened by activities like climbing stairs or sitting for long periods. Prepatellar bursitis involves swelling and redness directly in front of the kneecap, often due to prolonged kneeling or a direct blow.


What are the symptoms of gout or pseudogout in the knee?

Gout or pseudogout in the knee can cause sudden and severe pain, swelling, redness, and warmth in the joint. These symptoms are due to the accumulation of uric acid crystals (gout) or calcium pyrophosphate crystals (pseudogout) in the joint.


What home remedies can help alleviate knee pain and swelling?

Home remedies for knee pain and swelling include resting the knee, applying ice packs for 15-20 minutes every few hours, elevating the leg above heart level, and using over-the-counter pain relievers like ibuprofen to reduce inflammation and pain.


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