[37F] With neck lump, chest discomfort, and hoarseness

Patient Description

A 37-year-old female presents with a hard, tender lump in the front of her neck that has been gradually increasing in size over the past week. She also reports hoarseness and frequent throat clearing. Additionally, she has been experiencing right-sided chest discomfort and tightness for several days, rated as a 5 out of 10 in severity, with no known alleviating or exacerbating factors. The patient has felt very tired recently and has had constipation but no changes in appetite or significant weight changes. She has a family history of thyroid disease and cancer and had an MRI recently, unrelated to her current symptoms. She does not currently smoke or use tobacco products. Her medical history includes obesity, diagnosed several years ago, and a hysterectomy. Current medications include Diamox (500mg twice a day), Prozac (40mg once a day), and Doxepin (10mg nightly). She also takes Tylenol as needed and has no known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Thyroid Nodule or Goiter: A lump in the neck that is hard and gradually increasing in size could be a thyroid nodule or goiter. Thyroid nodules are common and can sometimes cause symptoms like hoarseness, throat clearing, and tenderness. Given your family history of thyroid disease and cancer, this is a significant possibility.

    • Typical Treatments and Testing: An ultrasound of the thyroid and blood tests to check thyroid function (TSH, T3, T4) are common initial tests. Depending on the results, a fine-needle aspiration biopsy may be needed to rule out cancer. Treatment can range from monitoring to medication or surgery, depending on the cause and severity.
  • Thyroiditis: Inflammation of the thyroid gland can cause a tender lump in the neck, hoarseness, and fatigue. Thyroiditis can be due to autoimmune conditions, infections, or other causes.

    • Typical Treatments and Testing: Blood tests to check for thyroid antibodies and inflammation markers, as well as an ultrasound, are common. Treatment may include anti-inflammatory medications, thyroid hormone replacement, or other specific treatments based on the underlying cause.
  • Lymphadenopathy: Enlarged lymph nodes in the neck can present as a lump and may be tender. This can be due to infections, inflammation, or more serious conditions like lymphoma.

    • Typical Treatments and Testing: A physical examination, blood tests, and imaging studies like an ultrasound or CT scan can help determine the cause. Treatment depends on the underlying condition and may include antibiotics, anti-inflammatory medications, or more specific treatments.
  • Chest Discomfort and Tightness: This could be related to anxiety, musculoskeletal issues, or other conditions. Given the presence of a neck lump and hoarseness, it is important to rule out any related conditions.

    • Typical Treatments and Testing: A thorough physical examination, chest X-ray, and possibly an ECG (electrocardiogram) to rule out cardiac causes. Treatment will depend on the underlying cause.

What you can do

While waiting to see a healthcare provider, you can try the following to help manage your symptoms:

  1. Monitor the Lump: Keep track of any changes in the size, shape, or tenderness of the lump. Note any new symptoms like difficulty swallowing or breathing.
  2. Stay Hydrated: Drink plenty of water to help with throat clearing and overall well-being.
  3. Manage Constipation: Increase your fiber intake through fruits, vegetables, and whole grains. Stay hydrated and consider over-the-counter remedies if needed.
  4. Rest and Manage Fatigue: Ensure you get adequate rest and manage stress levels. Gentle exercise can also help improve energy levels.
  5. Use MDandMe: Journal your symptoms, track progress, and get insights. This can help you provide detailed information to your healthcare provider.

What you should look out for

Seek medical attention more urgently if you experience any of the following:

  • Rapid increase in the size of the lump
  • Difficulty breathing or swallowing
  • Severe or worsening chest pain
  • Unexplained weight loss
  • Persistent fever or night sweats

Remember, while this information can help you understand your symptoms, it is important to consult a healthcare professional for a formal diagnosis and appropriate treatment.

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3 mo ago


People Also Ask


What are the common causes of a hard, tender lump in the neck?

Common causes of a hard, tender lump in the neck include thyroid nodules, goiter, thyroiditis, and lymphadenopathy. These can be due to various factors such as autoimmune conditions, infections, or more serious conditions like cancer.


How can thyroid nodules affect my voice and throat?

Thyroid nodules can affect your voice and throat by pressing on the vocal cords or surrounding structures, leading to symptoms like hoarseness and frequent throat clearing.


What tests are typically done to diagnose thyroid issues?

To diagnose thyroid issues, doctors typically perform an ultrasound of the thyroid and blood tests to check thyroid function, including TSH, T3, and T4 levels. Depending on the results, a fine-needle aspiration biopsy may be needed.


What should I do if I experience chest discomfort along with a neck lump?

If you experience chest discomfort along with a neck lump, it's important to seek medical evaluation to rule out any related conditions. Tests like a chest X-ray or ECG may be conducted to determine the cause, and treatment will depend on the underlying issue.

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