[33M] With abdominal pain and elevated AST

Patient Description

A 33-year-old male presents with dull abdominal pain located just below the ribcage on the right side, persisting for three weeks. The pain occasionally peaks every 30 minutes to an hour, lasting 5-10 minutes. Accompanying symptoms include nausea and weight loss. Recent blood tests indicate elevated AST levels. The patient has ceased alcohol consumption and reports no changes in bowel movements or stool appearance. There is no jaundice, dark urine, fever, chills, or itching. The patient has a history of high blood pressure, diagnosed in 2020, and is currently on Lisinopril and hydrochlorothiazide. No new medications or supplements have been started, and there is no recent travel to areas endemic for hepatitis. No known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you've provided, here are some possible explanations for your symptoms:

  • Liver-related issues: The combination of right upper abdominal pain, nausea, weight loss, and elevated AST levels could suggest a liver condition. Elevated AST (aspartate aminotransferase) is an enzyme that can indicate liver inflammation or damage. Conditions such as fatty liver disease, hepatitis, or liver cirrhosis could be possibilities, especially considering your recent cessation of alcohol consumption. It's important to follow up with a healthcare provider for further evaluation and testing, which may include liver function tests, imaging studies like an ultrasound, or other diagnostic procedures.

  • Gallbladder issues: Pain in the right upper abdomen that comes and goes could also be related to gallbladder problems, such as gallstones or inflammation (cholecystitis). These conditions can cause similar symptoms, including nausea and changes in liver enzyme levels. An ultrasound of the abdomen is often used to diagnose gallbladder issues.

  • Pancreatic issues: Although less common, pancreatic conditions such as pancreatitis can cause abdominal pain and elevated liver enzymes. This is more likely if there is a history of alcohol use, but it can occur for other reasons as well.

What you can do

  1. Consult a healthcare provider: It's important to see a doctor for a thorough evaluation. They can perform necessary tests to determine the cause of your symptoms and elevated AST levels.

  2. Monitor your symptoms: Keep track of your symptoms, including any changes in pain, nausea, or other new symptoms. This information can be helpful for your healthcare provider.

  3. Maintain a healthy lifestyle: Continue to avoid alcohol, as it can exacerbate liver issues. Eat a balanced diet rich in fruits, vegetables, and whole grains, and stay hydrated.

  4. Use MDandMe: Consider using the MDandMe app to journal your symptoms, track your progress, and share your medical notes with your healthcare provider. This can help in managing your condition and providing valuable information during your medical visits.

What you should look out for

Seek medical attention promptly if you experience any of the following:

  • Severe or worsening abdominal pain
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine or pale stools
  • Persistent vomiting or inability to keep food down
  • Fever or chills

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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1 mo ago

People Also Ask


What could cause elevated AST levels in blood tests?

Elevated AST levels can indicate liver inflammation or damage. Common causes include liver conditions such as hepatitis, fatty liver disease, or cirrhosis. It can also be elevated due to muscle damage, heart issues, or other organ inflammation.


How can liver-related issues manifest in terms of symptoms?

Liver-related issues can manifest as right upper abdominal pain, nausea, weight loss, and elevated liver enzymes. In more severe cases, symptoms may include jaundice, dark urine, and pale stools.


What are common symptoms of gallbladder problems?

Common symptoms of gallbladder problems include right upper abdominal pain that may come and go, nausea, vomiting, and sometimes changes in liver enzyme levels. Pain may occur after eating fatty meals.


When should someone with abdominal pain seek immediate medical attention?

Immediate medical attention should be sought if there is severe or worsening abdominal pain, jaundice, dark urine, pale stools, persistent vomiting, or if fever and chills develop.


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