[33F] With sore throat, swollen lymph nodes, and respiratory symptoms post-COVID-19

Patient Description

A 33-year-old female presents with a sore throat and swollen lymph nodes for the past three days. She also reports nasal congestion with yellow mucus, a moderate cough for one week, and a fever with a recorded temperature of 100.6°F. The cough worsens when mucus comes up or if she gets hot. Additionally, she experiences chest pain described as pressure and some wheezing, but no shortness of breath. She has no history of asthma or other lung conditions. The patient has known allergies to sulfa and sulfa drugs and is currently taking Suboxone (2 doses of 8mg sublingual per day) and Goody Powders (4 sticks a day). She was recently exposed to someone with COVID-19 and tested positive herself over a week ago, but these symptoms are new. Her family history includes heart disease, diabetes, and cancer. No other pre-existing conditions or chronic illnesses are reported.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

  • Upper Respiratory Infection (URI): This is a common condition that includes infections like the common cold or viral pharyngitis. Symptoms often include a sore throat, swollen lymph nodes, cough, nasal congestion, and fever. Yellow mucus can indicate a bacterial component or simply the body's immune response to a viral infection.

    • Treatment: Typically, URIs are managed with rest, hydration, and over-the-counter medications to relieve symptoms. Antibiotics are not effective against viral infections but may be prescribed if a bacterial infection is suspected.
  • COVID-19: Given your recent positive test, it's possible that your symptoms are related to COVID-19. COVID-19 can cause a wide range of symptoms, including sore throat, cough, fever, and chest pressure.

    • Treatment: Mild cases are usually managed at home with rest, fluids, and over-the-counter medications. Severe cases may require medical attention.
  • Sinusitis: This is an inflammation of the sinuses that can cause nasal congestion, yellow mucus, sore throat, and cough. It can be viral or bacterial.

    • Treatment: Treatment may include decongestants, saline nasal sprays, and, in some cases, antibiotics if a bacterial infection is suspected.
  • Strep Throat: This is a bacterial infection that can cause a severe sore throat, swollen lymph nodes, and fever. It is less likely given the presence of cough and nasal congestion, which are more common in viral infections.

    • Treatment: Strep throat is treated with antibiotics. A rapid strep test or throat culture can confirm the diagnosis.

What you can do

While it's important to consult a healthcare provider for a formal diagnosis and treatment plan, here are some steps you can take to alleviate your symptoms:

  1. Stay Hydrated: Drink plenty of fluids like water, herbal teas, and broths to stay hydrated and soothe your throat.
  2. Rest: Ensure you get plenty of rest to help your body fight off the infection.
  3. Over-the-Counter Medications: Use over-the-counter pain relievers like acetaminophen or ibuprofen to reduce fever and relieve sore throat pain. Decongestants and saline nasal sprays can help with nasal congestion.
  4. Warm Salt Water Gargle: Gargling with warm salt water can help soothe a sore throat.
  5. Humidifier: Using a humidifier can add moisture to the air and help ease congestion and coughing.
  6. Monitor Symptoms: Keep track of your symptoms using the MDandMe journal. This can help you and your healthcare provider understand the progression of your illness and make informed decisions about your care.

What you should look out for

Seek medical attention if you experience any of the following:

  • Difficulty Breathing: If you develop shortness of breath or difficulty breathing, seek immediate medical attention.
  • Persistent Chest Pain: If the chest pressure worsens or becomes severe, consult a healthcare provider.
  • High Fever: If your fever persists or exceeds 102°F, it may indicate a more serious infection.
  • Worsening Symptoms: If your symptoms worsen or do not improve after a few days, consult a healthcare provider.
  • New or Severe Symptoms: If you develop new symptoms like confusion, severe headache, or a rash, seek medical attention.

Remember, while this advice can help you manage your symptoms, it is not a substitute for professional medical care. Please consult a healthcare provider for a formal diagnosis and treatment plan.

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6 mo ago

Top picked over-the-counter products for Sore Throat: At-Home Management

People Also Ask


What are the common symptoms of an upper respiratory infection (URI)?

Common symptoms of an upper respiratory infection include a sore throat, swollen lymph nodes, cough, nasal congestion, and fever. Yellow mucus can also be present, indicating either a bacterial component or the body's immune response to a viral infection.


How can I differentiate between COVID-19 symptoms and a common cold?

COVID-19 and the common cold can share symptoms like a sore throat, cough, and fever. However, COVID-19 may also include symptoms like loss of taste or smell, more severe respiratory issues, and fatigue. A COVID-19 test is the most reliable way to differentiate between the two.


When should I consider seeing a doctor for sinusitis?

You should consider seeing a doctor for sinusitis if your symptoms persist for more than 10 days, if you have a high fever, or if you experience severe facial pain or swelling. A doctor can determine if antibiotics are necessary if a bacterial infection is suspected.


What are the risks of untreated strep throat?

Untreated strep throat can lead to complications such as rheumatic fever, which can affect the heart, or kidney inflammation. It is important to seek medical treatment if strep throat is suspected, as antibiotics can effectively treat the infection and prevent complications.


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