[31M] With tingling and burning sensations after taking supplements

Patient Description

A 31-year-old male experienced tingling sensations in his arms, hands, and legs approximately 5 hours after taking a vitamin B pill, a vitamin D pill, and a magnesium supplement. The patient also reported a warm, burning sensation near his chest and head for the past hour. Additional symptoms include dizziness and changes in bowel movements, such as both diarrhea and constipation. The patient denies muscle weakness, difficulty moving limbs, changes in vision or hearing, nausea, vomiting, and chest pain. He is currently taking Zoloft (25 mg daily) and Flexeril (a muscle relaxer). The patient has not consumed any alcohol, caffeine, or recreational drugs recently and does not have any pre-existing medical conditions or chronic illnesses. There have been no recent changes to his diet or exposure to new environments, chemicals, or allergens.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Supplement Overload or Interaction: Taking multiple supplements at once, especially for the first time, can sometimes lead to unexpected side effects. The combination of vitamin B, vitamin D, and magnesium might be causing your tingling sensations, burning feelings, dizziness, and gastrointestinal issues. Some people can be more sensitive to certain vitamins and minerals, especially in high doses.

    • Typical Treatments: Usually, the symptoms will resolve on their own once the supplements are out of your system. However, if symptoms persist, a healthcare provider might recommend stopping the supplements or adjusting the dosage.
  • Magnesium Overdose: High doses of magnesium supplements can cause gastrointestinal issues like diarrhea and constipation, as well as symptoms like dizziness and tingling sensations.

    • Typical Treatments: Discontinuing the magnesium supplement and staying hydrated can help alleviate symptoms. In severe cases, medical intervention might be necessary.
  • Anxiety: Anxiety can sometimes manifest with physical symptoms such as tingling, burning sensations, and gastrointestinal issues. Since you mentioned taking Zoloft, which is often prescribed for anxiety or depression, it's possible that anxiety could be contributing to your symptoms.

    • Typical Treatments: Managing anxiety through medication, therapy, and lifestyle changes can help. If you think your anxiety is worsening, consult your healthcare provider.

What you can do

  1. Stop Taking the Supplements: Discontinue the vitamin B, vitamin D, and magnesium supplements for now. Monitor your symptoms to see if they improve.
  2. Stay Hydrated: Drink plenty of water to help flush out any excess vitamins and minerals from your system.
  3. Consult Your Healthcare Provider: It's important to discuss these symptoms with your doctor, especially since you are on Zoloft and Flexeril. They can provide a formal assessment and recommend any necessary tests or adjustments to your medication.
  4. Use MDandMe: Journal your symptoms, track your progress, and get insights using the MDandMe app. This can help you and your healthcare provider understand your condition better and make informed decisions.

What you should look out for

Seek medical attention more urgently if you experience:

  • Severe or worsening chest pain
  • Difficulty breathing
  • Severe dizziness or fainting
  • Persistent or worsening gastrointestinal issues
  • Any new or worsening symptoms

Remember, while I can provide some guidance, it's crucial to consult a healthcare professional for a formal diagnosis and appropriate treatment.

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6 mo ago

People Also Ask


Can taking multiple supplements at once cause side effects?

Yes, taking multiple supplements at once can lead to unexpected side effects, especially if they are taken in high doses or if the individual is sensitive to certain vitamins and minerals. It's important to monitor for any adverse reactions and consult a healthcare provider if symptoms occur.


What are the symptoms of magnesium overdose?

Symptoms of magnesium overdose can include gastrointestinal issues such as diarrhea and constipation, as well as dizziness, tingling sensations, and in severe cases, more serious symptoms like difficulty breathing or irregular heartbeat. It's important to discontinue use and seek medical advice if these symptoms occur.


How can anxiety manifest physically in the body?

Anxiety can manifest physically with symptoms such as tingling sensations, burning feelings, dizziness, and gastrointestinal issues. These physical symptoms can sometimes be mistaken for other medical conditions, so it's important to consider anxiety as a potential cause, especially if there is a history of anxiety or related medication use.


What should I do if I experience tingling sensations after taking supplements?

If you experience tingling sensations after taking supplements, it's advisable to stop taking the supplements and monitor your symptoms. Staying hydrated can help flush out excess vitamins and minerals. If symptoms persist or worsen, consult a healthcare provider for further evaluation and guidance.


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