[28F] With progressive neurological and systemic symptoms

What might be happening

Based on the symptoms you've described, several potential diagnoses could explain your condition. Here are some possibilities:

1. Multiple Sclerosis (MS):

   • Rationale: MS is a condition where the immune system attacks the protective sheath (myelin) that covers nerve fibers, causing communication problems between your brain and the rest of your body. Symptoms like blurred vision, pins and needles, fatigue, muscle spasms, urinary retention, slurred speech, confusion, loss of coordination, weak grip, dizziness, vertigo, muscle weakness, numbness, trouble concentrating, trouble swallowing, and loss of appetite can all be associated with MS.
   • Typical Treatments/Testing: Diagnosis often involves MRI scans, lumbar puncture, and evoked potential tests. Treatment may include corticosteroids, disease-modifying therapies, and physical therapy.

2. Peripheral Neuropathy:

   • Rationale: This condition results from damage to the peripheral nerves and can cause symptoms like numbness, tingling, burning sensations, and muscle weakness. It can be caused by diabetes, infections, traumatic injuries, and exposure to toxins.
   • Typical Treatments/Testing: Blood tests, nerve conduction studies, and electromyography (EMG) are commonly used for diagnosis. Treatment focuses on managing the underlying cause and may include medications like gabapentin, physical therapy, and lifestyle changes.

3. Systemic Lupus Erythematosus (SLE):

   • Rationale: SLE is an autoimmune disease that can affect multiple systems in the body, including the nervous system. Symptoms like fatigue, muscle weakness, confusion, and urinary issues can be part of its presentation.
   • Typical Treatments/Testing: Blood tests for specific antibodies, urine tests, and imaging studies are used for diagnosis. Treatment often involves immunosuppressive drugs and anti-inflammatory medications.

What you can do

Loss of Sensation and Muscle Weakness:

• See a doctor as soon as possible: Given the severity and progression of your symptoms, it's crucial to consult a healthcare provider for a thorough evaluation. They may refer you to a neurologist for specialized testing.
• At home: Keep a journal of your symptoms, noting when they occur and any potential triggers. This can help your healthcare provider make a more accurate diagnosis.

Dizziness and Vertigo:

• See a doctor: These symptoms can be debilitating and may indicate a serious underlying condition. Your doctor may recommend vestibular rehabilitation therapy or medications to manage these symptoms.
• At home: Avoid sudden movements and try to sit or lie down when you feel dizzy. Staying hydrated and avoiding caffeine and alcohol can also help.

Urinary Retention:

• See a doctor: This symptom can lead to complications like urinary tract infections. Your doctor may perform tests to determine the cause and recommend treatments such as medications or catheterization.
• At home: Monitor your fluid intake and try to urinate at regular intervals to prevent bladder overdistension.

Trouble Swallowing:

• See a doctor: Difficulty swallowing can lead to nutritional deficiencies and other complications. Your doctor may refer you to a speech therapist or recommend a swallowing study.
• At home: Eat soft, easy-to-swallow foods and take small bites. Avoid foods that are difficult to chew or swallow.

Fatigue and Loss of Appetite:

• See a doctor: These symptoms can be part of a larger systemic issue. Your doctor may recommend blood tests to check for nutritional deficiencies or other underlying conditions.
• At home: Try to eat small, frequent meals that are high in nutrients. Rest as needed and avoid overexertion.

Mental Health:

• See a doctor: The combination of physical symptoms and sleep deprivation can take a toll on your mental health. Your doctor may recommend counseling or medications to help manage anxiety and sleep issues.
• At home: Practice relaxation techniques like deep breathing or meditation. Keeping a regular sleep schedule can also help improve your sleep quality.

What you should look out for

Given the complexity and severity of your symptoms, it's important to seek medical care as soon as possible. Reasons to seek care even more urgently include:

• Sudden worsening of symptoms
• New symptoms like shortness of breath, chest pain, or severe headaches
• Fainting or severe dizziness
• Difficulty breathing or swallowing

Remember, while I can provide information and suggestions, it's crucial to consult a healthcare provider for a formal diagnosis and treatment plan. You can also use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.