[25F] Experiencing widespread swelling and gastrointestinal symptoms

Patient Description

A 25-year-old female has been experiencing gradual onset of swelling in various parts of her body, including her wrists, thighs, stomach, neck, and eyelids, over the past two weeks. The swelling is painful and causes weakness, particularly after 12-hour night shifts at her new job. She has tried muscle relaxer cream and ibuprofen without relief. Additionally, she reports black stool, diarrhea, and nausea, and has seen blood in her stool, though she is currently on her period. She has no history of gastrointestinal issues, liver disease, or kidney problems. She occasionally consumes alcohol and was pre-diabetic in her youth. She has had migraines since the age of 8-9. She is currently taking ibuprofen every other day and has no known allergies to medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential diagnoses to consider:

  1. Edema (Fluid Retention):

    • Explanation: The swelling in your wrists, thighs, stomach, neck, and eyelids could be due to fluid retention. This can be caused by various conditions, including heart, liver, or kidney problems. Given that the swelling worsens after long periods of standing, it might be related to venous insufficiency, where blood doesn't flow back to the heart efficiently.
    • Typical Treatments/Testing: Your doctor might recommend blood tests, urine tests, and imaging studies like an ultrasound to determine the cause of the edema. Treatment often involves addressing the underlying cause, reducing salt intake, and possibly using diuretics (medications that help remove excess fluid).
  2. Gastrointestinal Bleeding:

    • Explanation: Black stool (melena) can indicate bleeding in the upper gastrointestinal tract. This, combined with diarrhea and nausea, suggests that there might be an issue such as a peptic ulcer or gastritis.
    • Typical Treatments/Testing: Your doctor might recommend a stool test, blood tests, and possibly an endoscopy to visualize the inside of your gastrointestinal tract. Treatment could involve medications to reduce stomach acid, antibiotics if an infection is present, and lifestyle changes.

What you can do

Swelling and Pain:

  • See a doctor as soon as possible: Given the extent and duration of your swelling, it's important to get a thorough evaluation. Your doctor can determine the underlying cause and recommend appropriate treatment.
  • Elevate your legs: When you're resting, try to keep your legs elevated to help reduce swelling.
  • Compression stockings: Wearing compression stockings can help improve blood flow and reduce swelling in your legs.
  • Stay hydrated: Drink plenty of water, as dehydration can sometimes worsen swelling.

Black Stool and Gastrointestinal Symptoms:

  • Seek immediate medical attention: Black stool can be a sign of gastrointestinal bleeding, which requires prompt evaluation. Your doctor will likely perform tests to determine the source of the bleeding.
  • Avoid NSAIDs: Medications like ibuprofen can irritate the stomach lining and potentially worsen bleeding. Discuss alternative pain relief options with your doctor.

General Tips:

  • Monitor your symptoms: Keep track of your symptoms, including when they occur and any potential triggers. This information can be helpful for your doctor.
  • Use MDandMe: You can use MDandMe to journal your symptoms, track your progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Given the severity of your symptoms, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Shortness of breath: This could indicate a more serious underlying condition, such as heart or lung problems.
  • Severe abdominal pain: This could be a sign of a serious gastrointestinal issue.
  • Fainting or dizziness: This could indicate a significant drop in blood pressure or other serious conditions.
  • Persistent or worsening symptoms: If your symptoms continue to worsen despite home remedies, seek medical attention promptly.

Remember, while I can provide information and suggestions, it's important to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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3 mo ago


People Also Ask


What could be causing the swelling in various parts of my body?

The swelling, or edema, could be due to fluid retention caused by conditions such as heart, liver, or kidney problems, or venous insufficiency. It's important to see a doctor for tests to determine the exact cause.


Why is my stool black, and should I be concerned?

Black stool, known as melena, can indicate bleeding in the upper gastrointestinal tract, which is a serious condition that requires immediate medical attention to identify and treat the source of bleeding.


Can ibuprofen cause gastrointestinal issues like bleeding?

Yes, ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can irritate the stomach lining and potentially cause gastrointestinal bleeding, especially if taken frequently or in high doses.


What lifestyle changes can help manage my symptoms?

To manage symptoms, consider elevating your legs to reduce swelling, wearing compression stockings, staying hydrated, and avoiding NSAIDs like ibuprofen. It's also important to monitor your symptoms and seek medical advice for a tailored treatment plan.

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