[21M] With recurrent swollen lymph nodes and fatigue

Patient Description

A 21-year-old male presents with recurrent swollen lymph nodes in the back of the neck, primarily on the left side, causing headaches and pressure on the eyes. These symptoms have been occurring off and on for the past 3 to 4 months, with increased frequency to almost daily in the last two weeks. The lymph nodes feel like hard lumps and can last up to a week, though they are sometimes alleviated by massage and Tylenol. The patient also reports extreme fatigue, nasal congestion, a feeling of a lump in the throat, and overall malaise. He rarely experiences a runny nose, but his nose is almost always stuffed, especially worse in the mornings. He reports poor sense of smell and facial pain or pressure around the sinuses. The patient has a history of GERD, which is mostly controlled with diet and lifestyle changes, and has experienced pneumonia four years in a row in the past. There is no known history of respiratory allergies, chronic sinusitis, or autoimmune diseases, and no recent exposure to new environments or irritants. No current medications or known drug allergies are reported.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, there are a few potential explanations for what you might be experiencing:

  1. Chronic Sinusitis or Allergic Rhinitis: Your symptoms of nasal congestion, facial pressure, and a feeling of a lump in your throat could be related to chronic sinusitis or allergic rhinitis. These conditions can cause persistent nasal congestion and post-nasal drip, which might explain the sensation in your throat. The fact that your symptoms are worse in the morning could suggest an environmental trigger, such as dust mites or mold in your sleeping area.

  2. Lymphadenopathy: The swollen lymph nodes in your neck that cause headaches and pressure on your eyes could be due to a chronic infection or inflammation. Since you have a history of recurrent pneumonia, it's possible that your immune system is reacting to a lingering infection or inflammation.

  3. GERD-Related Symptoms: Although you mentioned that your GERD is mostly under control, it's possible that some of your symptoms, like the lump in your throat, could be related to acid reflux. GERD can sometimes cause extra-esophageal symptoms, such as throat irritation and post-nasal drip.

  4. Fatigue and Malaise: Your extreme fatigue and overall malaise could be related to a combination of factors, including poor sleep quality due to nasal congestion, chronic inflammation, or an underlying condition that hasn't been identified yet.

What you can do

Nasal Congestion and Sinus Symptoms:

  • Consider using a saline nasal spray or rinse to help clear your nasal passages and reduce congestion.
  • Try using a humidifier in your bedroom to keep the air moist, which can help alleviate congestion.
  • Over-the-counter antihistamines or decongestants may provide relief, but consult with a healthcare professional before starting any new medication.

Swollen Lymph Nodes and Headaches:

  • Continue to manage your headaches with over-the-counter pain relievers like Tylenol, but be mindful of the recommended dosage.
  • Apply a warm compress to the affected area to help reduce swelling and discomfort.
  • Keep track of your symptoms using the MDandMe journal to identify any patterns or triggers.

Fatigue and Malaise:

  • Ensure you're getting adequate rest and maintaining a regular sleep schedule.
  • Engage in light physical activity, such as walking, to help boost your energy levels.
  • Stay hydrated and maintain a balanced diet to support your overall health.

What you should look out for

While your symptoms are concerning, they don't appear to be immediately life-threatening. However, you should seek medical attention if you experience any of the following:

  • Persistent or worsening symptoms despite self-care measures
  • New or unexplained symptoms, such as significant weight loss or night sweats
  • Difficulty breathing or swallowing
  • Severe or persistent headaches that don't respond to over-the-counter medication

It's important to consult with a healthcare professional to receive a formal diagnosis and appropriate treatment. They may recommend further testing, such as blood tests or imaging studies, to better understand the underlying cause of your symptoms.

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2 mo ago


People Also Ask


What could be causing recurrent swollen lymph nodes in the neck?

Recurrent swollen lymph nodes in the neck could be due to chronic infections, inflammation, or an immune response to a lingering infection. It's important to monitor the symptoms and consult a healthcare professional for a proper diagnosis.


How can nasal congestion and sinus pressure be managed at home?

Nasal congestion and sinus pressure can be managed at home by using saline nasal sprays or rinses, humidifiers to keep the air moist, and over-the-counter antihistamines or decongestants. However, it's advisable to consult a healthcare professional before starting any new medication.


Could GERD be contributing to the feeling of a lump in the throat?

Yes, GERD can sometimes cause extra-esophageal symptoms such as a sensation of a lump in the throat due to acid reflux irritating the throat. Managing GERD with diet and lifestyle changes can help alleviate these symptoms.


What are some potential causes of extreme fatigue and malaise?

Extreme fatigue and malaise can be caused by poor sleep quality due to nasal congestion, chronic inflammation, or an underlying condition. Ensuring adequate rest, maintaining a regular sleep schedule, and engaging in light physical activity can help improve energy levels.


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4 Comments


Anonymous#4896

2 mo ago

I had something similar happen after I got COVID.

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Arora (Bot)#28060

2 mo ago

I'm sorry to hear you went through that after having COVID. It's quite common for people to experience lingering symptoms that can be confusing and frustrating. It's important to monitor how you feel and stay in touch with your healthcare provider to address any ongoing concerns. I hope you're feeling better now, and if you have any tips or experiences that helped you recover, feel free to share them with others who might be in a similar situation! Take care. 😊

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Anonymous#4896

2 mo ago

Can Lymphadenopathy becaused by COVID?

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Arora (Bot)#28060

2 mo ago

Yes, lymphadenopathy, or swollen lymph nodes, can sometimes occur after a viral infection like COVID-19. It's your body's way of fighting off the infection, and in some cases, the swelling may persist even after other symptoms have resolved. If you notice persistent or worsening lymph node swelling, it's a good idea to consult with a healthcare professional to ensure everything is on track with your recovery. Stay well! 😊

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