[21F] With thumb pain, swelling, and stiffness

Patient Description

A 21-year-old female presents with a one-week history of pain, redness, swelling, and stiffness in the thumb, particularly at the first knuckle. The pain is described as aching and throbbing, rated 8 out of 10 in severity, and has made it difficult to move the thumb. The symptoms came on gradually and are worse in the morning and when cold. Additionally, a few other fingers are also swollen, red, or painful. The patient reports significant weight loss of 30 lbs over the past six months and experiences morning stiffness lasting more than 30 minutes. There is no history of recent injury, fever, chills, fatigue, or loss of appetite. The patient smokes 4 cigarettes per day and has a history of diabetes, managed with 50 units of insulin before bed. No known allergies or other medications.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, here are some possible explanations:

  1. Rheumatoid Arthritis (RA):

    • Rationale: RA is an autoimmune condition that often presents with joint pain, swelling, and stiffness, particularly in the morning. It can affect multiple joints, including the fingers and thumbs. The gradual onset of symptoms and morning stiffness lasting more than 30 minutes are characteristic of RA.
    • Typical Treatments/Testing: Blood tests (e.g., rheumatoid factor, anti-CCP antibodies), imaging studies (X-rays, MRI), and physical examination by a rheumatologist. Treatment may include medications like DMARDs (disease-modifying antirheumatic drugs), NSAIDs, and corticosteroids.
  2. Infectious Arthritis:

    • Rationale: This condition can cause joint pain, swelling, and redness, often accompanied by fever. While you haven't reported a fever, the significant pain and swelling in your thumb and fingers could suggest an infection.
    • Typical Treatments/Testing: Blood tests, joint fluid analysis, and imaging studies. Treatment typically involves antibiotics and sometimes drainage of the infected joint.

What you can do

For Pain, Swelling, and Stiffness in Your Thumb and Fingers:

  • See a Doctor: Given the severity and duration of your symptoms, it's important to consult a healthcare provider as soon as possible. They can perform the necessary tests to determine the exact cause and recommend appropriate treatment.
  • At Home:
    • Rest and Protect Your Joints: Avoid activities that exacerbate the pain and swelling.
    • Apply Ice: Use an ice pack on the affected joints for 15-20 minutes several times a day to reduce swelling.
    • Over-the-Counter Pain Relief: Consider taking NSAIDs like ibuprofen (Advil) to help manage pain and inflammation, but be sure to follow the recommended dosage.
    • Gentle Exercises: Engage in gentle range-of-motion exercises to keep your joints flexible. Warm up your hands before exercises to reduce stiffness.
    • Warm Compresses: Use warm compresses or take warm baths to help relieve stiffness, especially in the morning.

For Weight Loss:

  • Monitor Your Diet: Ensure you are eating a balanced diet rich in nutrients. Unintentional weight loss can be a sign of an underlying condition that needs medical attention.
  • Consult a Doctor: Significant weight loss over a short period should be evaluated by a healthcare provider to rule out any serious conditions.

General Tips:

  • Quit Smoking: Smoking can exacerbate inflammation and delay healing. Consider seeking support to quit smoking.
  • Track Your Symptoms: Use MDandMe to journal your symptoms, track your progress, and share your medical notes with your healthcare provider.

What you should look out for

Given the severity of your symptoms and the potential for serious underlying conditions, you should seek medical care as soon as possible. Reasons to seek care even more urgently include:

  • Increased Pain or Swelling: If the pain or swelling worsens or spreads to other joints.
  • Fever or Chills: These could indicate an infection.
  • Difficulty Moving Joints: If you experience significant difficulty moving your joints or if they become very stiff.

Remember, while I can provide information and suggestions, it's crucial to consult a healthcare professional for a formal diagnosis and treatment plan.

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4 mo ago

People Also Ask


What are the common symptoms of rheumatoid arthritis?

Common symptoms of rheumatoid arthritis include joint pain, swelling, and stiffness, particularly in the morning or after periods of inactivity. It often affects multiple joints, such as the fingers, wrists, and knees, and can lead to fatigue and weight loss.


How can smoking affect joint health and inflammation?

Smoking can exacerbate inflammation and delay healing, potentially worsening joint pain and swelling. It may also increase the risk of developing rheumatoid arthritis and reduce the effectiveness of treatments.


What are some home remedies to alleviate joint pain and stiffness?

Home remedies for joint pain and stiffness include resting the affected joints, applying ice packs to reduce swelling, using warm compresses or taking warm baths to relieve stiffness, and performing gentle range-of-motion exercises to maintain flexibility.


When should I see a doctor for joint pain and swelling?

You should see a doctor for joint pain and swelling if the symptoms are severe, persistent, or worsening, if you experience morning stiffness lasting more than 30 minutes, or if you have other concerning symptoms like significant weight loss or fever.


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