[21F] With raised white bumps and peeling inside cheeks

Patient Description

A 21-year-old female has been experiencing raised white bumps on the inside of her lips and cheeks for about a month. These bumps are not painful or itchy and appeared gradually. Additionally, the lining of her cheeks is peeling, which she described as a line of rolled skin. She started taking Effexor (37.5 mg once per day) recently, and the bumps appeared after she began this medication. She also mentioned that she might have a dry mouth but is not certain. Occasionally, her gums hurt, but the pain goes away. She noticed a playdough taste when consuming almond milk and yogurt. There is a patch of red, broken skin on the inside of her cheek. She has not experienced any fever, general feeling of being unwell, swelling, or redness in her mouth or gums. She has no history of autoimmune diseases, recent travel, or exposure to new foods, drinks, or substances that might cause an allergic reaction. She is not taking any other medications, supplements, or herbal remedies, and she has no known allergies to medications.

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Arora's Assessment

What might be happening

Based on the information you have provided, here are some possible explanations for your symptoms:

  • Oral Lichen Planus: This is a chronic inflammatory condition that affects the mucous membranes inside your mouth. It can cause white, lacy patches, red swollen tissues, or open sores. The exact cause is unknown, but it may be related to an immune system response.

    • Treatment: Typically involves corticosteroids to reduce inflammation, and other medications to manage symptoms. Good oral hygiene and avoiding irritants like spicy foods can help.
  • Canker Sores (Aphthous Ulcers): These are small, shallow lesions that develop on the soft tissues in your mouth or at the base of your gums. They can be triggered by stress, minor mouth injuries, acidic or spicy foods, and certain medical conditions.

    • Treatment: Usually involves topical treatments to reduce pain and inflammation. Avoiding trigger foods and maintaining good oral hygiene can help.
  • Medication Side Effects: Effexor (venlafaxine) can sometimes cause dry mouth and other oral symptoms. The changes in your mouth might be a side effect of this medication.

    • Treatment: Discussing with your doctor about the side effects and possibly adjusting the dosage or switching medications.
  • Oral Thrush (Candidiasis): This is a fungal infection that can cause white patches in the mouth. It is more common in people with weakened immune systems or those taking certain medications.

    • Treatment: Antifungal medications are typically prescribed to treat oral thrush.

What you can do

While it's important to consult a healthcare professional for a formal diagnosis and treatment plan, here are some steps you can take in the meantime:

  1. Maintain Good Oral Hygiene: Brush your teeth at least twice a day and floss daily. Use a mild toothpaste and a soft-bristled toothbrush.
  2. Avoid Irritants: Stay away from spicy, acidic, or rough-textured foods that can irritate your mouth.
  3. Stay Hydrated: Drink plenty of water to help with dry mouth and overall oral health.
  4. Rinse with Salt Water: A saltwater rinse can help soothe your mouth. Mix 1/2 teaspoon of salt in a cup of warm water and rinse your mouth several times a day.
  5. Monitor Your Symptoms: Keep track of any changes in your symptoms and note any potential triggers. You can use MDandMe to journal your symptoms, track progress, get insights, and share longitudinal medical notes with your provider.

What you should look out for

Seek medical attention if you experience any of the following:

  • Increased Pain or Discomfort: If the bumps or peeling become painful or more bothersome.
  • Spreading or Worsening Symptoms: If the white bumps or peeling skin spread or worsen.
  • Difficulty Eating or Swallowing: If you have trouble eating or swallowing.
  • Fever or General Illness: If you develop a fever or feel generally unwell.

Remember, while I can provide information and suggestions, it's important to consult a healthcare professional for a formal diagnosis and appropriate treatment.

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3 mo ago


People Also Ask


What are the common symptoms of oral lichen planus?

Common symptoms of oral lichen planus include white, lacy patches on the mucous membranes, red swollen tissues, or open sores in the mouth. It may also cause discomfort or a burning sensation.


Can Effexor cause oral symptoms like dry mouth or white bumps?

Yes, Effexor (venlafaxine) can cause oral symptoms such as dry mouth, which might lead to other oral changes like white bumps. It's important to discuss these side effects with your doctor.


What are the typical treatments for canker sores?

Typical treatments for canker sores include topical treatments to reduce pain and inflammation, such as mouth rinses, pastes, or gels. Avoiding trigger foods and maintaining good oral hygiene can also help.


How can I differentiate between oral thrush and other oral conditions?

Oral thrush typically presents as creamy white lesions on the tongue or inner cheeks, which can be wiped away to reveal red tissue underneath. It is often accompanied by a cottony feeling in the mouth and loss of taste. A healthcare professional can provide a definitive diagnosis.


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