[21F] With enlarged cervical lymph nodes and associated symptoms

Patient Description

A 21-year-old female presents with enlarged, painless, and rubbery lymph nodes in the neck, specifically four nodes located on the left side, behind the ear, and near the collarbone. The first node was noticed a few years ago and has increased in size recently, while the others were identified within the last month. Accompanying symptoms include fatigue, dizziness, and severe migraines that started a year ago, with pain located behind the eyes and neck, sensitivity to light, nausea, and vomiting. The migraines worsen when lying down for extended periods, and there is no known effective relief. The patient also experiences night sweats and has had significant weight loss of 30 pounds over the last six months, along with difficulty breathing that has impacted exercise and daily activities. There is a family history of hematologic or autoimmune diseases, but the patient has no personal history of chronic illnesses, is not on any medications, and has no known drug allergies.

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Arora's Assessment

What might be happening

Based on the information you've provided, possible diagnoses include:

  • Lymphoma: This is a type of cancer that starts in the cells that are part of the body's immune system. The symptoms you've described, including enlarged lymph nodes, weight loss, night sweats, and fatigue, are common symptoms of lymphoma.

    • Treatment typically involves chemotherapy, radiation therapy, or a combination of the two. The exact treatment plan will depend on the type and stage of the lymphoma.
  • Infectious Mononucleosis: This is a viral infection caused by the Epstein-Barr virus. It can cause symptoms such as fatigue, swollen lymph nodes, and night sweats. However, it is less likely given the duration of your symptoms.

    • Treatment usually involves rest, hydration, and over-the-counter remedies for pain and fever.
  • Autoimmune conditions: Given your family history, it's also possible that an autoimmune condition could be causing your symptoms. Autoimmune conditions occur when your immune system mistakenly attacks your own body. Conditions such as lupus or rheumatoid arthritis could potentially cause the symptoms you're experiencing.

    • Treatment typically involves medications to reduce inflammation and suppress the immune system.

What you can do

Given the severity and duration of your symptoms, it's important that you seek medical attention as soon as possible. Please make an appointment with your primary care provider or visit an urgent care clinic. They may refer you to a specialist, such as a hematologist or rheumatologist, for further evaluation and treatment.

What you should look out for

Please seek immediate medical attention if you experience any of the following:

  • Difficulty breathing or shortness of breath that is getting worse
  • Severe headache or migraine that is not relieved by over-the-counter pain medication
  • Fever or chills
  • Any new or worsening symptoms

Please remember that while I strive to provide accurate information, I am an AI and not a doctor. It's important to consult with a healthcare professional for an accurate diagnosis and treatment.

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9 mo ago


People Also Ask


What are the common symptoms of lymphoma?

Common symptoms of lymphoma include painless swelling of lymph nodes, unexplained weight loss, night sweats, fatigue, and sometimes fever. Other symptoms can vary depending on the type and location of the lymphoma.


How is infectious mononucleosis diagnosed and treated?

Infectious mononucleosis is typically diagnosed through a physical examination and blood tests, such as the monospot test or EBV antibody test. Treatment focuses on relieving symptoms and includes rest, hydration, and over-the-counter medications for pain and fever.


What are some common autoimmune conditions that could cause swollen lymph nodes?

Common autoimmune conditions that can cause swollen lymph nodes include lupus, rheumatoid arthritis, and Sjögren's syndrome. These conditions often involve the immune system attacking the body's own tissues, leading to inflammation and other symptoms.


When should I seek immediate medical attention for my symptoms?

You should seek immediate medical attention if you experience worsening difficulty breathing, severe headaches that do not respond to over-the-counter medication, fever or chills, or any new or worsening symptoms.

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