[20F] With involuntary foot/toe movements and associated symptoms

Patient Description

A 20-year-old female has been experiencing involuntary movements in her feet and toes for about six months, which come and go. These movements seem to be triggered by taking Adderall. She also reports leg weakness, diarrhea, brain fog, memory issues, and a fast heartbeat. Her feet and upper right leg hurt, with the pain persisting even when she hasn't walked much. The involuntary movements can last several hours and usually subside after sleep. Additionally, she has been experiencing headaches, blurred vision, and numbness or tingling in her feet. She also reports chest pain and discomfort. She uses alcohol and cocaine about once a week, but not always with Adderall. Recently, she noticed a weight gain of about 5 pounds and had some spotting before her last menstrual cycle, which is unusual for her. Her past medical history includes ADHD, diagnosed at age 11, and an allergy to penicillin. She is currently taking Hydroxyzine 65 mg at night and Adderall 50-60 mg about 7 days a month. No other medications, supplements, or over-the-counter drugs are being taken.

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Arora's Assessment

What might be happening

Based on the symptoms you've described, several potential diagnoses could explain your condition. Here are some possibilities:

Involuntary Movements, Leg Weakness, and Foot Pain

  • Restless Legs Syndrome (RLS): This condition can cause an uncontrollable urge to move your legs, often accompanied by uncomfortable sensations. It can be triggered or worsened by medications like Adderall.
  • Peripheral Neuropathy: This condition involves damage to the peripheral nerves and can cause pain, tingling, and weakness in your feet and legs. It can be exacerbated by substance use, including alcohol and cocaine.

Diarrhea and Fast Heartbeat

  • Side Effects of Adderall: Adderall can cause gastrointestinal issues like diarrhea and cardiovascular symptoms like a fast heartbeat.
  • Substance Use: Cocaine and alcohol can also contribute to these symptoms, especially when used in combination with Adderall.

Brain Fog, Memory Issues, and Zoning Out

  • ADHD and Medication Effects: Both ADHD and its treatment with Adderall can contribute to cognitive symptoms like brain fog and memory issues.
  • Substance Use: The use of alcohol and cocaine can also impair cognitive function and contribute to these symptoms.

Blurred Vision and Chest Pain

  • Side Effects of Adderall: Blurred vision and chest pain can be side effects of Adderall, especially at higher doses.
  • Cardiovascular Issues: Given your fast heartbeat and chest pain, it's important to rule out any underlying cardiovascular issues.

What you can do

Involuntary Movements, Leg Weakness, and Foot Pain

  • Consult Your Doctor: It's important to discuss these symptoms with your healthcare provider, especially since they may be related to your Adderall use.
  • Lifestyle Changes: Reducing or eliminating the use of alcohol and cocaine can help alleviate these symptoms.
  • Symptom Tracking: Use MDandMe to journal your symptoms, track progress, and share this information with your healthcare provider.

Diarrhea and Fast Heartbeat

  • Medication Review: Talk to your doctor about the side effects of Adderall and whether a dosage adjustment or alternative medication might be appropriate.
  • Hydration: Ensure you stay well-hydrated, especially if you are experiencing diarrhea.
  • Avoid Stimulants: Try to avoid other stimulants, including caffeine, which can exacerbate a fast heartbeat.

Brain Fog, Memory Issues, and Zoning Out

  • Cognitive Exercises: Engage in activities that stimulate your brain, such as puzzles or reading.
  • Healthy Lifestyle: Ensure you get adequate sleep, maintain a balanced diet, and exercise regularly.
  • Symptom Tracking: Use MDandMe to document your cognitive symptoms and any potential triggers.

Blurred Vision and Chest Pain

  • Immediate Medical Attention: Given the severity of these symptoms, seek medical attention as soon as possible to rule out any serious conditions.
  • Medication Review: Discuss with your doctor whether your current medications could be contributing to these symptoms.

What you should look out for

Given the complexity and severity of your symptoms, it's important to seek medical care as soon as possible. Here are some specific signs that warrant immediate attention:

  • Severe Chest Pain: If you experience severe or worsening chest pain, seek emergency medical care.
  • Severe Headache or Vision Changes: If your headaches become severe or your vision significantly worsens, seek medical attention.
  • Severe Weakness or Numbness: If you experience severe weakness or numbness in your legs or feet, seek medical care.

Remember, while I can provide information and suggestions, it's crucial to consult with a healthcare professional for a formal diagnosis and appropriate treatment.

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2 mo ago


People Also Ask


Can Adderall cause involuntary movements or restless legs syndrome?

Yes, Adderall can cause or exacerbate involuntary movements and conditions like restless legs syndrome, especially at higher doses or in sensitive individuals.


What are the potential side effects of combining Adderall with alcohol and cocaine?

Combining Adderall with alcohol and cocaine can increase the risk of cardiovascular issues, exacerbate side effects like fast heartbeat and chest pain, and impair cognitive functions.


How can Adderall affect cognitive functions like memory and concentration?

Adderall can affect cognitive functions by improving focus and attention in individuals with ADHD, but it can also cause side effects like brain fog and memory issues, especially if not used as prescribed.


What should I do if I experience chest pain and blurred vision while taking Adderall?

If you experience chest pain and blurred vision while taking Adderall, it's important to seek immediate medical attention to rule out serious cardiovascular issues and discuss medication adjustments with your doctor.


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