[19F] Experiencing widespread joint pain, fatigue, and neurological symptoms

Question

I have negative results for all rheumatoid conditions and lupus. I'm not sure what it could be. The only positive test was anti-SSA at a 1.2 (very borderline positive) and my doctor said she can't diagnose me with anything. Does anyone know what this might be?

Patient Description

A 19-year-old female has been experiencing widespread joint pain, particularly in the knees, hands, elbows, neck, and hips, described as a dull ache with a severity rated at 7 out of 10. The joint pain, present for four years, is somewhat alleviated by heating pads and is accompanied by warmth in the affected joints. Additionally, the patient reports experiencing fatigue, dizziness, particularly in hot weather or when standing up quickly, and a spinning sensation that leads to nausea. The patient also describes constant brain fog, affecting concentration and memory, and a malar rash on the face that is warm and tingly, which has been present for a year. Other symptoms include low-grade fevers and cold extremities. The patient has a history of Tourette's, anxiety, PTSD, depression, and Mitral Valve Prolapse, diagnosed in childhood. Current medications include atomoxetine, fluoxetine, Lamictal, and Seroquel, with no reported side effects, and a weekly dose of 50,000 IU of Vitamin D. The patient denies any allergies, sudden weight loss, hair loss, chest pain, shortness of breath, severe headaches, or changes in vision, aside from headaches that do not respond to medication.

Show More

Arora's Assessment

What might be happening

Based on the symptoms you've described, a few conditions could be considered:

  • Systemic Lupus Erythematosus (SLE): This is an autoimmune disease that can cause a wide range of symptoms, including joint pain, fatigue, skin rashes (including a malar or "butterfly" rash), and cognitive difficulties (often referred to as "brain fog"). SLE can also cause sensitivity to sunlight, which could explain your rash worsening in the sun, and low-grade fevers. However, a negative ANA test makes this diagnosis less likely, as most people with SLE have a positive ANA.

  • Fibromyalgia: This is a chronic condition characterized by widespread pain, fatigue, and cognitive difficulties. It does not typically cause a rash, but some people with fibromyalgia are more sensitive to environmental factors, which could potentially explain your skin reactions.

  • Chronic Fatigue Syndrome (CFS): This condition is characterized by extreme fatigue that doesn't improve with rest and can be worsened by physical or mental activity. Other symptoms can include joint pain, headaches, and difficulty concentrating.

  • Postural Orthostatic Tachycardia Syndrome (POTS): This is a condition that affects circulation and can cause dizziness upon standing, fatigue, and brain fog. It's often associated with conditions like fibromyalgia and chronic fatigue syndrome.

Please note that these are potential explanations for your symptoms, but only a healthcare provider can provide a definitive diagnosis.

What you can do

  1. Keep a symptom diary: This can help you and your healthcare provider identify any patterns or triggers for your symptoms.

  2. Stay hydrated and maintain a balanced diet: This can help manage symptoms like dizziness and fatigue.

  3. Gentle exercise: While it's important not to overdo it, regular gentle exercise like walking or swimming can help manage joint pain and fatigue.

  4. Rest: Make sure you're getting enough sleep and taking time to rest during the day if needed.

  5. Consult a healthcare provider: It's important to discuss your symptoms with a healthcare provider who can provide a diagnosis and appropriate treatment.

What you should look out for

  • Any new symptoms or a significant worsening of your existing symptoms.
  • Symptoms like chest pain, shortness of breath, or severe headaches, which could indicate a more serious condition and should be evaluated immediately.
  • Any changes in your mood or mental health. Chronic illnesses can often have an impact on mental health, and it's important to seek help if you're feeling depressed or anxious.

Remember, while I strive to provide accurate information, I'm not a doctor and this advice should not replace a consultation with a healthcare provider.

Show More

4
 Hugs
4
 Comments

Save

10 mo ago

Top picked over-the-counter products for Tingling or Cold Sensations at the Back of Your Head

People Also Ask


What are the common symptoms of Systemic Lupus Erythematosus (SLE)?

Common symptoms of SLE include joint pain, fatigue, skin rashes (such as a malar rash), sensitivity to sunlight, low-grade fevers, and cognitive difficulties like brain fog. Diagnosis often involves blood tests, including ANA, and a clinical evaluation by a healthcare provider.


How is Fibromyalgia diagnosed and managed?

Fibromyalgia is diagnosed based on a history of widespread pain lasting more than three months, along with other symptoms like fatigue and cognitive difficulties. Management includes medications, physical therapy, stress reduction, and lifestyle changes such as regular exercise and a healthy diet.


What lifestyle changes can help manage Chronic Fatigue Syndrome (CFS)?

Lifestyle changes for managing CFS include maintaining a balanced diet, staying hydrated, pacing activities to avoid overexertion, getting regular, gentle exercise, and ensuring adequate rest and sleep. Cognitive behavioral therapy and graded exercise therapy may also be recommended.


What is Postural Orthostatic Tachycardia Syndrome (POTS) and how is it treated?

POTS is a condition that affects circulation, causing symptoms like dizziness upon standing, fatigue, and brain fog. Treatment often includes increasing fluid and salt intake, wearing compression garments, and medications to help manage heart rate and blood pressure. Lifestyle changes like avoiding prolonged standing and staying hydrated are also important.


Preview

Post

4 Comments


Leo#3962

10 mo ago

Your symptoms sound most consistent with Lupus, which is a clinical diagnosis (in other words, lab tests are helpful but not strictly necessary). According to the 2019 EULAR/ACR classification criteria for systemic lupus (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827566/) it seems pretty likely that you do have lupus based on your description. I would suggest asking for a second opinion and if possible seeing a rheumatologist who will be more experienced.

Some additional labs relevant for the Lupus criteria by the way are low complement proteins (specifically C3 and C4), high protein count in urine, low white blood cell count, and low platelets

2
 Hugs
Reply

Leo#3962

10 mo ago

Also, the treatment for many autoimmune diseases is similar (usually involving steroids or other medications that calm down your immune system). So, even without a definitive diagnosis, it is possible that your doctor may recommend a trial period for a treatment to see if symptoms improve.

2
 Hugs
Reply
Owner

Anonymous#9630

10 mo ago

thank you! I had my complement proteins checked as well as lupus coagulant factor and platelets checked and they are all normal (which is good, but also gives no answer). My rheumatologist said because of the labs, she can't diagnose lupus or any autoimmune diseases. So I guess it's still unknown for now. :/

1
 Hugs
Reply

Leo#3962

10 mo ago

Ah I see. Darn, that's unfortunate. So I guess for now it's "functional neurosensory disorder of unknown etiology"

2
 Hugs
Reply

Share your feedback